SCHEMBL5953097

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5951681	0.86	SMN1; SMN2 (0.47)	HPSESMN1; SMN2KDM4EMAPK1ALDH1A1
	SCHEMBL5951486	0.86	HPSE (0.60)	HPSESMN1; SMN2ITKKDM4EGAA
	SCHEMBL5952921	0.86	HPSE (0.47)	HPSEITKKDM4EALDH1A1RAB9A
	SCHEMBL5951506	0.83	HPSE (0.45)	HPSESMN1; SMN2CYP1A2CYP3A4CYP2D6
	SCHEMBL13374046	0.83	MMP2 (0.48)	HPSEMAPK1MAPT
	SCHEMBL5952107	0.82	HPSE (0.50)	HPSESMN1; SMN2KDM4EALDH1A1POLB
	SCHEMBL5951652	0.81	HPSE (0.43)	HPSESMN1; SMN2KDM4EMAPK1ALDH1A1
	SCHEMBL4826377	0.81	AURKA (0.51)	SMN1; SMN2ITKROCK2ROCK1KDM4E
	SCHEMBL5953713	0.80	HPSE (0.49)	HPSESMN1; SMN2KDM4EGAAALDH1A1
	SCHEMBL5953012	0.79	HPSE (0.47)	HPSESMN1; SMN2ITKKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.