SCHEMBL5953358

SCHEMBL5953358

Cc1ccccc1N(c1ccc(C=Cc2ccc(N(c3ccccc3C)c3ccccc3C)cc2)cc1)c1ccccc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.48
CTDSP1 Q9GZU7 1/20 0.41
APP P05067 6/20 0.40
RAB9A P51151 4/20 0.37
MEN1 O00255 3/20 0.37
NPC1 O15118 3/20 0.37
KMT2A Q03164 3/20 0.37
MAPT P10636 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 1/20 0.37
STAT3 P40763 1/20 0.37
HTT P42858 1/20 0.37
INSR P06213 1/20 0.37
ALOX15 P16050 1/20 0.37
CASP1 P29466 1/20 0.37
HBB P68871 1/20 0.37
TTR P02766 1/20 0.37
ALOX5 P09917 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5943062 1.00 RELA (0.48) RELACTDSP1APPRAB9AMEN1
SCHEMBL452801 0.96 RELA (0.55) RELACTDSP1APPALDH1A1TTR
SCHEMBL13358717 0.94 RELA (0.44) RELACTDSP1APPRAB9AMEN1
SCHEMBL14526484 0.94 RELA (0.44) RELACTDSP1APPRAB9AMEN1
SCHEMBL13358228 0.94 RELA (0.48) RELACTDSP1APPMEN1KMT2A
SCHEMBL13372139 0.94 RELA (0.48) RELACTDSP1APPRAB9AMEN1
SCHEMBL4923203 0.93 RELA (0.43) RELACTDSP1APPRAB9AMEN1
SCHEMBL18417178 0.92 RELA (0.55) RELACTDSP1APPALDH1A1TTR
SCHEMBL4316561 0.91 RELA (0.42) RELACTDSP1APPRAB9AMEN1
SCHEMBL8187099 0.91 ALOX5 (0.45) RELACTDSP1APPRAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7147938-B2 Organic element for electroluminescent devices EASTMAN KODAK COMPANY (US) 2006-12-12 US disclosed
US-20060003183-A1 Light emitting diodes with light emitting layers containing a stilbene derivative and a boron complex having an absorption spectrum that overlaps with the emission spectrum of the stilbene derivative; improved brightness EASTMAN KODAK COMPANY 2006-01-05 US disclosed