Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16393791 | 0.81 | GABRA1 (0.39) | PNMT | |
| SCHEMBL5953900 | 0.79 | ADRA2A (0.40) | PNMT | |
| SCHEMBL2975173 | 0.79 | GABRA1 (0.33) | — | |
| SCHEMBL4035804 | 0.77 | CYP2A6 (0.36) | CYP1A2CYP2A6 | |
| SCHEMBL30477217 | 0.77 | CYP2A6 (0.36) | CYP1A2CYP2A6 | |
| SCHEMBL7053653 | 0.77 | GABRA1 (0.36) | CYP1A2 | |
| SCHEMBL7056142 | 0.77 | HTR2A (0.40) | — | |
| SCHEMBL5953689 | 0.76 | HTR2A (0.39) | CYP1A2PNMT | |
| SCHEMBL1583270 | 0.75 | DPP4 (0.39) | PNMT | |
| SCHEMBL9075727 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105654-A | Curable resin mixture, curable resin composition, and cured product thereof | 日本化药株式会社 | 2020-12-18 | — | — | CN | disclosed |
| WO-2020031935-A1 | CURABLE RESIN MIXTURE, CURABLE RESIN COMPOSITION, AND CURED PRODUCT | 日本化薬株式会社 | 2020-02-13 | — | — | WO | disclosed |
| US-20060052620-A1 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2006-03-09 | — | — | US | disclosed |
| CN-1653021-A | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | CN | disclosed |
| EP-1492749-A1 | PREPARATION OF SUBSTITUTED INDENES | Basell Polyolefine GmbH (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084904-A1 | PREPARATION OF SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |
| EP-0985674-B1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS | MITSUBISHI CHEM CORP (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0773204-B1 | Process for the preparation of an indene and use thereof for the preparation of metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2002-12-04 | — | — | EP | disclosed |
| US-6255515-B1 | COORDINATION POLYMERIZATION CATALYSTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0985674-A1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0617044-B1 | Process for preparing cyclopentadienyl group-containing silicon compound or cyclopentadienyl group-containing germanium compound | MITSUI CHEMICALS INC (JP) | 1999-01-20 | — | — | EP | disclosed |
| EP-0530647-B1 | Metallocenes, catalysts containing these and process for the manufacture of olefinic polymers by using these catalysts | HOECHST AG (DE) | 1998-01-28 | — | — | EP | disclosed |
| EP-0773204-A2 | Process for the preparation of an indene and use thereof for the preparation of metallocenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-14 | — | — | EP | disclosed |
| US-5360921-A | REACTING LITHIUM, SODIUM OR POTASSIUM SALT OF A CYCLOPENTADIENE DERIVATIVE WITH A SILICON OR GERMANIUM HALIDE COMPOUND IN THE PRESENCE OF A CYANIDE OR A THIOCYANATE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0617044-A2 | Process for preparing cyclopentadienyl group-containing silicon compound or cyclopentadienyl group-containing germanium compound | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |
| US-5329033-A | Metallocene catalyst, indene containing ligands, alumoxane cocatalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| US-5278264-A | Catalytic polymerizing in presence of a transition metal metallocene | HOECHST AG (DE) | 1994-01-11 | — | — | US | disclosed |
| EP-0530647-A1 | Metallocenes, catalysts containing these and process for the manufacture of olefinic polymers by using these catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052620-A1 | Preparation of substituted indenes | INTS9, CYP1A2, INF2 | CYP1A2 2/4885CYP2A6 95/4885PNMT 480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.