Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KDM4B | O94953 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953469 | 0.78 | HTR1A (0.38) | PTGDR2 | |
| SCHEMBL5954172 | 0.77 | PSMB5 (0.35) | PSMB5PTGDR2NR1I2KDM4BCHRM1 | |
| SCHEMBL5954147 | 0.71 | — | — | |
| SCHEMBL294290 | 0.64 | KDM4E (0.46) | PSMB5PTGDR2NR1I2KDM4BCHRM1 | |
| SCHEMBL2334220 | 0.64 | KDM4E (0.46) | PSMB5PTGDR2NR1I2KDM4BCHRM1 | |
| SCHEMBL10956529 | 0.64 | KDM4E (0.46) | PSMB5PTGDR2NR1I2KDM4BCHRM1 | |
| Methane SCHEMBL11206867 | 0.63 | KDM4E (0.45) | PSMB5PTGDR2NR1I2KDM4BCHRM1 | |
| SCHEMBL6397545 | 0.63 | KDM4E (0.39) | PSMB5PTGDR2NR1I2KDM4BCHRM1 | |
| SCHEMBL36429 | 0.62 | KDM4E (0.43) | PSMB5PTGDR2NR1I2KDM4BCHRM1 | |
| SCHEMBL11423479 | 0.62 | PSMB5 (0.42) | PSMB5PTGDR2NR1I2KDM4BCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052620-A1 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052620-A1 | Preparation of substituted indenes | INTS9, CYP1A2, INF2 | PSMB5 1624/4885PTGDR2 1991/4885NR1I2 2022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.