SCHEMBL5953580

SCHEMBL5953580

[CH2]c1cc(CCC)ccc1CCC

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.45
CNR2 P34972 1/20 0.45
ALOX5 P09917 2/20 0.43
LPL P06858 1/20 0.38
LIPG Q9Y5X9 1/20 0.38
GABRA1 P14867 3/20 0.37
GABRB2 P47870 3/20 0.37
THRB P10828 2/20 0.36
CA2 P00918 1/20 0.35
MGLL Q99685 1/20 0.33
PLK1 P53350 1/20 0.33
SKP2 Q13309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9100129 0.83 CNR1 (0.45) CNR1CNR2ALOX5LPLLIPG
SCHEMBL9740304 0.79 CNR1 (0.50) CNR1CNR2ALOX5LPLLIPG
SCHEMBL1069410 0.78 CNR1 (0.45) CNR1CNR2ALOX5LPLLIPG
SCHEMBL16959716 0.78 TAAR1 (0.41)
SCHEMBL8963358 0.78 CNR1 (0.45) CNR1CNR2ALOX5LPLLIPG
SCHEMBL16959425 0.77 LMNA (0.37)
SCHEMBL16956886 0.77 EDNRB (0.37)
SCHEMBL16956502 0.77 KCNH2 (0.42)
SCHEMBL5255675 0.77 CNR1 (0.44) CNR1CNR2ALOX5LPLLIPG
SCHEMBL5048783 0.76 CNR1 (0.47) CNR1CNR2ALOX5LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7064139-B2 Method for treating retroviral infections UNIROYAL CHEMICAL COMPANY, INC. (US) 2006-06-20 US disclosed
CN-1036064-C Benzene derivatives having NGF production-promoting activity SANKYO CO (JP) 1997-10-08 CN disclosed
US-5643925-A COGNITION ACTIVATORS AND NERVE GROWTH FACTORS SANKYO COMPANY, LIMITED (JP) 1997-07-01 US disclosed
US-5614521-A NERVE GROWTH FACTOR SANKYO COMPANY, LIMITED (JP) 1997-03-25 US disclosed
EP-0501656-B1 New benzene derivatives having (NGF) production-promoting activity SANKYO CO (JP) 1997-01-22 EP disclosed
CN-1064273-A The new NGF that has generates the active benzene derivative of promotion SANKYO CO (JP) 1992-09-09 CN disclosed
EP-0501656-A2 New benzene derivatives having (NGF) production-promoting activity Sankyo Company Limited (JP) 1992-09-02 EP disclosed