Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2539422 | 0.83 | SKP2 (0.46) | CNR1CNR2SKP2FFAR4LPL | |
| SCHEMBL598650 | 0.79 | CNR1 (0.50) | CNR1CNR2SKP2FFAR4LPL | |
| SCHEMBL5953580 | 0.78 | CNR1 (0.45) | CNR1CNR2SKP2LPLLIPG | |
| Hydrochloric Acid SCHEMBL2446312 | 0.76 | SKP2 (0.47) | CNR1CNR2SKP2FFAR4LPL | |
| SCHEMBL1263571 | 0.76 | CNR1 (0.47) | CNR1CNR2SKP2FFAR4LPL | |
| SCHEMBL9656290 | 0.74 | CNR1 (0.45) | CNR1CNR2SKP2FFAR4LPL | |
| SCHEMBL9100129 | 0.74 | CNR1 (0.45) | CNR1CNR2LPLLIPGTHRB | |
| SCHEMBL14268146 | 0.74 | CNR1 (0.45) | CNR1CNR2SKP2FFAR4LPL | |
| SCHEMBL20918900 | 0.74 | SKP2 (0.46) | CNR1CNR2SKP2FFAR4LPL | |
| SCHEMBL8338503 | 0.74 | SIGMAR1 (0.47) | CNR1CNR2SKP2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8349843-B2 | Carboxylic acid derivatives, their preparation and use | ABBOTT GMBH & CO. KG (DE) | 2013-01-08 | — | — | US | disclosed |
| US-7863445-B2 | Carboxylic acid derivatives, their preparation and use | ABBOTT GMBH & CO. KG (DE) | 2011-01-04 | — | — | US | disclosed |
| US-20100076188-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076188-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE | HCAR1, HCAR2, HCAR3 | CNR1 205/4885CNR2 478/4885SKP2 2872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.