SCHEMBL5953857

SCHEMBL5953857

C=C(C)C(=O)NCCc1cc[n+](Cc2cc(C[n+]3ccc(-c4cc[n+](Cc5cc(C[n+]6ccc(CCNC(=O)C(=C)C)cc6)cc(B(O)O)c5)cc4)cc3)cc(OBO)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10137204 0.96 BCHE (0.32) BCHEACHESMN1; SMN2
SCHEMBL2737198 0.90 ALDH1A1 (0.33) BCHEACHESMN1; SMN2
SCHEMBL12530098 0.86 ALDH1A1 (0.36) BCHEACHESMN1; SMN2
SCHEMBL14518742 0.84 NPC1 (0.32) BCHEACHESMN1; SMN2
SCHEMBL10137208 0.82 NPC1 (0.34) BCHEACHESMN1; SMN2
SCHEMBL10137077 0.76
SCHEMBL19194150 0.75
SCHEMBL13996865 0.75 BCHE (0.33) BCHEACHE
SCHEMBL13063338 0.70 NPC1 (0.32) BCHEACHESMN1; SMN2
SCHEMBL12249821 0.69 ENPP2 (0.41) BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9693720-B2 Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement MEDTRONIC MINIMED, INC. (US) 2017-07-04 US disclosed
US-20150080685-A1 EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT MEDTRONIC MINIMED, INC. (US) 2015-03-19 US disclosed
US-8983565-B2 Optical determination of pH and glucose MEDTRONIC MINIMED, INC. (US) 2015-03-17 US disclosed
US-8979790-B2 Use of an equilibrium sensor to monitor glucose concentration MEDTRONIC MINIMED, INC. (US) 2015-03-17 US disclosed
US-20140058225-A1 OPTICAL DETERMINATION OF PH AND GLUCOSE GLUMETRICS, INC. (US) 2014-02-27 US disclosed
US-20140018646-A1 USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL GLUMETRICS, INC. (US) 2014-01-16 US disclosed
US-8535262-B2 Use of an equilibrium intravascular sensor to achieve tight glycemic control GLUMETRICS, INC. (US) 2013-09-17 US disclosed
US-20120116191-A1 USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL GLUMETRICS, INC. (US) 2012-05-10 US disclosed