Quercetin

Quercetin

SCHEMBL5953872

O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12.O=c1c(O[C@@H]2O[C@H]([C@H](O)CO)[C@H](O)[C@H]2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 5/20 0.70
L3MBTL1 Q9Y468 3/20 0.70
KDM4E B2RXH2 9/20 0.69
GAA P10253 6/20 0.69
MAPT P10636 6/20 0.69
P4HB P07237 5/20 0.69
EPHX2 P34913 5/20 0.69
POLB P06746 5/20 0.69
MAOA P21397 4/20 0.69
XDH P47989 4/20 0.69
SLCO2B1 O94956 3/20 0.69
CA12 O43570 2/20 0.69
CA2 P00918 2/20 0.69
CA4 P22748 2/20 0.69
CA7 P43166 2/20 0.69
ALPI P09923 2/20 0.69
LMNA P02545 2/20 0.69
ADRA2C P18825 2/20 0.69
KDM1A O60341 2/20 0.69
HMGB1 P09429 2/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30772268 0.97 AKR1B1 (0.74) AKR1B1L3MBTL1KDM4EGAAMAPT
SCHEMBL21408655 0.97 AKR1B1 (0.74) AKR1B1L3MBTL1KDM4EGAAMAPT
SCHEMBL24608 0.97 AKR1B1 (0.74) AKR1B1L3MBTL1KDM4EGAAMAPT
Water SCHEMBL21836718 0.96 AKR1B1 (0.73) AKR1B1L3MBTL1KDM4EGAAMAPT
Acetone SCHEMBL11411008 0.93 AKR1B1 (0.70) AKR1B1L3MBTL1KDM4EGAAMAPT
Flavonol SCHEMBL1278210 0.92 AKR1B1 (0.61) AKR1B1L3MBTL1KDM4EGAAMAPT
Quercitrin SCHEMBL17628743 0.91 P4HB (0.81) AKR1B1L3MBTL1KDM4EGAAMAPT
SCHEMBL4650695 0.86 KDM4E (0.70) AKR1B1L3MBTL1KDM4EGAAMAPT
Rutin SCHEMBL22326122 0.85 KDM4E (0.85) AKR1B1L3MBTL1KDM4EGAAMAPT
Pelargonidin SCHEMBL1947941 0.85 AKR1B1 (0.58) AKR1B1L3MBTL1KDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3004336-B1 ENZYMES CATALYZING THE GLYCOSYLATION OF POLYPHENOLS UNIVERSITÄT HAMBURG (DE) 2017-03-29 EP disclosed
EP-3004336-A1 ENZYMES CATALYZING THE GLYCOSYLATION OF POLYPHENOLS Universität Hamburg (DE) 2016-04-13 EP disclosed
US-20160090578-A1 ENZYMES CATALYZING THE GLYCOSYLATION OF POLYPHENOLS UNIVERSITAET HAMBURG (DE) 2016-03-31 US disclosed
WO-2014191524-A1 ENZYMES CATALYZING THE GLYCOSYLATION OF POLYPHENOLS UNIVERSITÄT HAMBURG (DE) 2014-12-04 WO disclosed
US-20060099690-A1 Extraction, purification and conversion of flavonoids from plant biomass HER MAJESTY THE QUEEN IN RIGHT OF CANADA, AS REPRE (CA) 2006-05-11 US disclosed