Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 6/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | P4HB | P07237 | 7/20 | 0.60 |
| ▸ | GAA | P10253 | 6/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | MAOA | P21397 | 4/20 | 0.60 |
| ▸ | XDH | P47989 | 4/20 | 0.60 |
| ▸ | SLCO2B1 | O94956 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA4 | P22748 | 3/20 | 0.60 |
| ▸ | CA7 | P43166 | 3/20 | 0.60 |
| ▸ | ALPI | P09923 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.60 |
| ▸ | KDM1A | O60341 | 2/20 | 0.60 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quercetin SCHEMBL5953872 | 0.92 | AKR1B1 (0.70) | AKR1B1L3MBTL1KDM4EP4HBGAA | |
| SCHEMBL30772268 | 0.90 | AKR1B1 (0.74) | AKR1B1L3MBTL1KDM4EP4HBGAA | |
| SCHEMBL24608 | 0.90 | AKR1B1 (0.74) | AKR1B1L3MBTL1KDM4EP4HBGAA | |
| SCHEMBL21408655 | 0.90 | AKR1B1 (0.74) | AKR1B1L3MBTL1KDM4EP4HBGAA | |
| Water SCHEMBL21836718 | 0.89 | AKR1B1 (0.73) | AKR1B1L3MBTL1KDM4EP4HBGAA | |
| Acetone SCHEMBL11411008 | 0.87 | AKR1B1 (0.70) | AKR1B1L3MBTL1KDM4EP4HBGAA | |
| Quercitrin SCHEMBL7920286 | 0.86 | P4HB (0.80) | AKR1B1L3MBTL1KDM4EP4HBGAA | |
| Quercitrin SCHEMBL17628743 | 0.85 | P4HB (0.81) | AKR1B1L3MBTL1KDM4EP4HBGAA | |
| Reynoutrin SCHEMBL2284762 | 0.83 | KDM4E (0.59) | AKR1B1L3MBTL1KDM4EP4HBGAA | |
| Rutin SCHEMBL725793 | 0.81 | KDM4E (0.82) | AKR1B1L3MBTL1KDM4EP4HBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2624816-A2 | STIMULATION OF NEUROREGENERATION BY FLAVONOID GLYCOSIDES | Zenobi-Wong, Marcy (CH) | 2013-08-14 | — | — | EP | disclosed |
| US-20120087980-A1 | STIMULATION OF NEUROREGENERATION BY FLAVONOID GLYCOSIDES | ZENOBI-WONG MARCY (CH) | 2012-04-12 | — | — | US | disclosed |
| WO-2012047763-A2 | STIMULATION OF NEUROREGENERATION BY FLAVONOID GLYCOSIDES | ZENOBI-WONG MARCY (CH) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120087980-A1 | STIMULATION OF NEUROREGENERATION BY FLAVONOID GLYCOSIDES | GAP43, BDNF, NGF | AKR1B1 3495/4885L3MBTL1 4419/4885KDM4E 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.