⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441833 | 0.72 | — | — | |
| SCHEMBL5822649 | 0.67 | — | — | |
| SCHEMBL6854760 | 0.67 | — | — | |
| SCHEMBL3836561 | 0.62 | TDP1 (0.36) | — | |
| SCHEMBL17784007 | 0.62 | — | — | |
| SCHEMBL7159525 | 0.62 | — | — | |
| SCHEMBL2425219 | 0.62 | — | — | |
| SCHEMBL3897780 | 0.61 | — | — | |
| SCHEMBL4855314 | 0.60 | — | — | |
| Bromide SCHEMBL3425347 | 0.60 | TDP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132973-B | The preparation of the phosphorous acid diamide of purifying | 罗地亚经营管理公司 | 2018-10-16 | — | — | CN | claimed |
| CN-106132973-A | The preparation of the phosphorous acid diamide of purification | 罗地亚经营管理公司 | 2016-11-16 | — | — | CN | claimed |
| US-20210309690-A1 | OLIGONUCLEOTIDE SYNTHESIS | ROCHE INNOVATION CT COPENHAGEN AS (DK) | 2021-10-07 | — | — | US | disclosed |
| EP-3724205-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | Janssen Biotech, Inc. (US) | 2020-10-21 | — | — | EP | disclosed |
| CN-110198948-A | Novel glycoside compounds and its manufacturing method | 株式会社博纳克 | 2019-09-03 | — | — | CN | disclosed |
| WO-2019118839-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH, INC. (US) | 2019-06-20 | — | — | WO | disclosed |
| EP-3491002-A2 | SYNTHESIS OF OLIGONUCLEOTIDES COMPRISING ACHIRAL 3'-S- OR 5'-S-PHOSPHOROTHIOLATE INTERNUCLEOSIDE LINKAGE | Roche Innovation Center Copenhagen A/S (DK) | 2019-06-05 | — | — | EP | disclosed |
| CN-106132973-B | The preparation of the phosphorous acid diamide of purifying | 罗地亚经营管理公司 | 2018-10-16 | — | — | CN | disclosed |
| EP-3137476-A1 | LINKAGE MODIFIED OLIGOMERIC COMPOUNDS | Ionis Pharmaceuticals, Inc. (US) | 2017-03-08 | — | — | EP | disclosed |
| CN-106488926-A | Compound composition and method comprising heat-labile part | 生物研究技术公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-106467525-A | One kind prepares the synthetic method of the monomer of 3 ' sulfydryl nucleoside analogs | 于中生 | 2017-03-01 | — | — | CN | disclosed |
| WO-2000008042-A1 | AMINOOXY-MODIFIED NUCLEOSIDIC COMPOUNDS AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 2000-02-17 | — | — | WO | disclosed |
| EP-0977767-A1 | AMINOOXY-MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998035978-A9 | AMINOOXY-MODIFIED OLIGONUCLEOTIDES | — | 1999-01-14 | — | — | WO | disclosed |
| EP-0766688-A4 | SYNTHESIS OF OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 1998-12-30 | — | — | EP | disclosed |
| WO-1998035978-A1 | AMINOOXY-MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1998-08-20 | — | — | WO | disclosed |
| EP-0813539-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF 2'-O-SUBSTITUTED PYRIMIDINES AND OLIGOMERIC COMPOUNDS THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 1997-12-29 | — | — | EP | disclosed |
| EP-0766688-A1 | SYNTHESIS OF OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1997-04-09 | — | — | EP | disclosed |
| WO-1996027606-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF 2'-O-SUBSTITUTED PYRIMIDINES AND OLIGOMERIC COMPOUNDS THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 1996-09-12 | — | — | WO | disclosed |
| WO-1995032980-A1 | SYNTHESIS OF OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1995-12-07 | — | — | WO | disclosed |