⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275790 | 0.72 | — | — | |
| SCHEMBL6854760 | 0.72 | — | — | |
| SCHEMBL5954330 | 0.72 | — | — | |
| SCHEMBL3836561 | 0.67 | TDP1 (0.36) | — | |
| SCHEMBL3897780 | 0.65 | — | — | |
| SCHEMBL1551660 | 0.65 | — | — | |
| SCHEMBL2792564 | 0.65 | — | — | |
| SCHEMBL7122405 | 0.65 | — | — | |
| Bromide SCHEMBL3425347 | 0.64 | TDP1 (0.33) | — | |
| SCHEMBL1078973 | 0.64 | TDP1 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585147-B | MAP4K4 inhibitors | 帝国理工学院创新有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-112585147-A | MAP4K4 inhibitors | 帝国科技及医学学院 | 2021-03-30 | — | — | CN | disclosed |
| CN-108627647-B | Detection and quantification method of post-translational modification proteomics | 四川大学 | 2020-06-19 | — | — | CN | disclosed |
| WO-2011028218-A1 | PROCESS FOR TRIPHOSPHATE OLIGONUCLEOTIDE SYNTHESIS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-03-10 | — | — | WO | disclosed |
| EP-1409497-A2 | METHOD FOR PREPARATION OF LNA PHOSPHORAMIDITES | Santaris Pharma A/S (DK) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003006475-A2 | METHOD FOR PREPARATION OF LNA PHOSPHORAMIDITES | SANTARIS PHARMA A/S (DK) | 2003-01-23 | — | — | WO | disclosed |
| WO-1995019373-A1 | ANTIBODIES SPECIFIC FOR D-MYO-INOSITOL 1,4,5-TRISPHOSPHATE | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 1995-07-20 | — | — | WO | disclosed |
| US-5393912-A | D-myo-inositol 1,4,5-trisphosphate analogues | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 1995-02-28 | — | — | US | disclosed |
| WO-1993005176-A1 | IMPROVEMENTS IN OLIGONUCLEOTIDE PRIMERS AND PROBES | MEDICAL RESEARCH COUNCIL (GB) | 1993-03-18 | — | — | WO | disclosed |