Pyridine

Pyridine

SCHEMBL5954793

O=C(Cl)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1.c1ccncc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
TSHR P16473 2/20 0.56
CYP3A4 P08684 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
TP53 P04637 2/20 0.48
ALOX5 P09917 5/20 0.46
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
KDM4E B2RXH2 2/20 0.42
MITF O75030 1/20 0.42
AGTR1 P30556 1/20 0.42
OPRK1 P41145 1/20 0.42
HTT P42858 3/20 0.42
LMNA P02545 1/20 0.42
ATM Q13315 1/20 0.41
MAPT P10636 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL54880 0.86 ALDH1A1 (0.66) ALDH1A1TSHRCYP3A4SMN1; SMN2TP53
4-Nitrobenzoyl Chloride SCHEMBL3708337 0.83 ALDH1A1 (0.73) ALDH1A1TSHRCES2CES1L3MBTL1
SCHEMBL728757 0.82 ALDH1A1 (0.66) ALDH1A1TSHRCYP3A4SMN1; SMN2TP53
Benzoic Acid SCHEMBL9443302 0.80 ALDH1A1 (0.65) ALDH1A1TSHRCYP3A4SMN1; SMN2TP53
4-Nitrobenzoyl Chloride SCHEMBL28291421 0.80 ALDH1A1 (0.67) ALDH1A1TSHRCES2CES1L3MBTL1
SCHEMBL12501661 0.79 ALDH1A1 (0.58) ALDH1A1TSHRCYP3A4SMN1; SMN2TP53
SCHEMBL30917331 0.79 ALDH1A1 (0.58) ALDH1A1TSHRCYP3A4SMN1; SMN2TP53
SCHEMBL7596117 0.79 ALDH1A1 (0.58) ALDH1A1TSHRCYP3A4SMN1; SMN2TP53
SCHEMBL8590575 0.78 ALDH1A1 (0.90) ALDH1A1TSHRCYP3A4SMN1; SMN2TP53
SCHEMBL28815673 0.75 ALDH1A1 (0.58) ALDH1A1TSHRCYP3A4SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104177842-B Composite filled type polymer matrix heat-conducting plastic of a kind of ultrabranching polyamide and preparation method thereof 中山大学 2017-04-05 CN claimed
CN-104177842-A Hyperbranched polyamide composite filled polymer-based thermal conductive plastic and preparation method thereof UNIV SUN YAT SEN 2014-12-03 CN claimed
CN-109633041-B Method for measuring dihydrotestosterone in medicine by derivatization HPLC method 广东食品药品职业学院 2021-07-02 CN disclosed
CN-109633041-A The method that derivatization HPLC method measures protona in drug 广东食品药品职业学院 2019-04-16 CN disclosed
CN-104177842-B Composite filled type polymer matrix heat-conducting plastic of a kind of ultrabranching polyamide and preparation method thereof 中山大学 2017-04-05 CN disclosed
CN-104177842-A Hyperbranched polyamide composite filled polymer-based thermal conductive plastic and preparation method thereof UNIV SUN YAT SEN 2014-12-03 CN disclosed
US-7115706-B2 Polyether polymers and compositions derived therefrom BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2006-10-03 US disclosed
US-20050209430-A1 Polyether polymers and compositions derived therefrom BOARD OF TRUSTEES MICHIGAN STATE UNIVERSITY (US) 2005-09-22 US disclosed