Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 19/20 | 0.83 |
| ▸ | CXCR1 | P25024 | 5/20 | 0.83 |
| ▸ | NT5E | P21589 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687691 | 0.91 | CXCR2 (1.00) | CXCR2CXCR1NT5ECYP2C9 | |
| SCHEMBL18953416 | 0.82 | CXCR2 (0.82) | CXCR2CXCR1NT5ECYP2C9 | |
| SCHEMBL18953534 | 0.81 | CXCR2 (1.00) | CXCR2CXCR1NT5E | |
| SCHEMBL18953372 | 0.80 | CXCR2 (0.66) | CXCR2CXCR1NT5ECYP2C9 | |
| SCHEMBL5955084 | 0.79 | CXCR2 (1.00) | CXCR2CXCR1CYP2C9 | |
| SCHEMBL5954935 | 0.76 | CXCR2 (1.00) | CXCR2CXCR1CYP2C9 | |
| SCHEMBL18953437 | 0.76 | CXCR2 (0.72) | CXCR2CXCR1NT5E | |
| SCHEMBL29843937 | 0.76 | CXCR2 (1.00) | CXCR2CXCR1CYP2C9 | |
| SCHEMBL18953522 | 0.76 | CXCR2 (0.72) | CXCR2CXCR1NT5E | |
| SCHEMBL4687748 | 0.76 | CXCR2 (0.60) | CXCR2CXCR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060122173-A1 | Il-8 receptor antagonists | BUSCH-PETERSEN JAKOB | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122173-A1 | Il-8 receptor antagonists | CXCL8, CCR8, IL1RN | CXCR2 9/4885CXCR1 13/4885NT5E 1108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.