Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.74 |
| ▸ | NT5E | P21589 | 5/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | TOP2A | P11388 | 1/20 | 0.69 |
| ▸ | RELA | Q04206 | 1/20 | 0.69 |
| ▸ | CA9 | Q16790 | 4/20 | 0.66 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.65 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.63 |
| ▸ | CETP | P11597 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112807 | 0.92 | PTGES (0.83) | PTGESNT5EPTPN1USP2LMNA | |
| SCHEMBL10214430 | 0.92 | PTGES (0.83) | PTGESNT5EPTPN1USP2LMNA | |
| SCHEMBL2733537 | 0.92 | PTGES (0.83) | PTGESNT5EPTPN1USP2LMNA | |
| SCHEMBL14345008 | 0.92 | PTGES (0.83) | PTGESNT5EPTPN1USP2LMNA | |
| SCHEMBL214200 | 0.92 | PTGES (0.83) | PTGESNT5EPTPN1USP2LMNA | |
| Water SCHEMBL8584387 | 0.91 | PTGES (0.82) | PTGESNT5EPTPN1USP2LMNA | |
| SCHEMBL13855630 | 0.90 | PTGES (0.72) | PTGESNT5EPTPN1USP2LMNA | |
| SCHEMBL13573803 | 0.90 | NT5E (0.75) | PTGESNT5EPTPN1USP2LMNA | |
| SCHEMBL5454249 | 0.90 | NT5E (0.75) | PTGESNT5EPTPN1USP2LMNA | |
| SCHEMBL554507 | 0.89 | PRKCD (0.80) | PTGESNT5EPTPN1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014730-A1 | Anti-fungal formulation of triterpene and essential oil | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2005-01-20 | — | — | US | claimed |
| WO-2004089357-A2 | ANTI-FUNGAL FORMULATION OF TRITERPENE AND ESSENTIAL OIL | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2004-10-21 | — | — | WO | claimed |
| EP-1322661-A1 | TRITERPENES HAVING FUNGICIDAL ACTIVITY AGAINST YEAST | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-07-02 | — | — | EP | claimed |
| US-20020128210-A1 | Triterpenes having human antifungal and antiyeast activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-09-12 | — | — | US | claimed |
| WO-2002026761-A1 | TRITERPENES HAVING FUNGICIDAL ACTIVITY AGAINST YEAST | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | claimed |
| US-20060003948-A1 | Compositions that include a triterpene and a carrier | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2006-01-05 | — | — | US | disclosed |
| WO-2005077377-A1 | COMPOSITIONS THAT INCLUDE A TRITERPENE AND A CARRIER | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2005-08-25 | — | — | WO | disclosed |
| US-20050014730-A1 | Anti-fungal formulation of triterpene and essential oil | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2005-01-20 | — | — | US | disclosed |
| WO-2004089357-A2 | ANTI-FUNGAL FORMULATION OF TRITERPENE AND ESSENTIAL OIL | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2004-10-21 | — | — | WO | disclosed |
| US-6642217-B2 | Treating a fungal or yeast infection such as with betulin, allobetulin, and lupeol | NATURTEK, LLC | 2003-11-04 | — | — | US | disclosed |
| EP-1322661-A1 | TRITERPENES HAVING FUNGICIDAL ACTIVITY AGAINST YEAST | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-07-02 | — | — | EP | disclosed |
| US-20020128210-A1 | Triterpenes having human antifungal and antiyeast activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-09-12 | — | — | US | disclosed |
| WO-2002026761-A1 | TRITERPENES HAVING FUNGICIDAL ACTIVITY AGAINST YEAST | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128210-A1 | Triterpenes having human antifungal and antiyeast activity | ERG28, LSS, MANBA | PTGES 1150/4885NT5E 1530/4885PTPN1 4365/4885 |
| US-20050014730-A1 | Anti-fungal formulation of triterpene and essential oil | BET1, VRK1, VRK2 | PTGES 183/4885NT5E 1732/4885PTPN1 3052/4885 |
| US-20060003948-A1 | Compositions that include a triterpene and a carrier | PGGT1B, BET1, CYP51A1 | PTGES 856/4885NT5E 1569/4885PTPN1 2655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.