Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10682086 | 0.95 | LMNA (0.58) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL597385 | 0.83 | — | — | |
| SCHEMBL312723 | 0.78 | SLC22A6 (0.65) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL1289888 | 0.78 | SLC22A6 (0.65) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL19925 | 0.78 | SLC22A6 (0.65) | TSHRSLC22A6LMNANFKB1PMP22 | |
| Glutarate SCHEMBL8855094 | 0.76 | SLC22A6 (0.85) | TSHRSLC22A6LMNANFKB1PMP22 | |
| Glutarate SCHEMBL9583826 | 0.76 | SLC22A6 (0.85) | TSHRSLC22A6LMNANFKB1PMP22 | |
| Glutarate SCHEMBL1480809 | 0.76 | SLC22A6 (0.85) | TSHRSLC22A6LMNANFKB1PMP22 | |
| Glutarate SCHEMBL8678828 | 0.76 | SLC22A6 (0.85) | TSHRSLC22A6LMNANFKB1PMP22 | |
| Glutarate SCHEMBL6701735 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014730-A1 | Anti-fungal formulation of triterpene and essential oil | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2005-01-20 | — | — | US | claimed |
| WO-2004089357-A2 | ANTI-FUNGAL FORMULATION OF TRITERPENE AND ESSENTIAL OIL | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2004-10-21 | — | — | WO | claimed |
| US-20040097436-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-05-20 | — | — | US | claimed |
| US-6689767-B2 | TRITERPENE BACTERICIDES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-02-10 | — | — | US | claimed |
| EP-1322661-A1 | TRITERPENES HAVING FUNGICIDAL ACTIVITY AGAINST YEAST | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-07-02 | — | — | EP | claimed |
| US-20020128210-A1 | Triterpenes having human antifungal and antiyeast activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-09-12 | — | — | US | claimed |
| US-20020119935-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-08-29 | — | — | US | claimed |
| WO-2002026762-A1 | TRITERPENES HAVING ANTIBACTERIAL ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | claimed |
| WO-2002026761-A1 | TRITERPENES HAVING FUNGICIDAL ACTIVITY AGAINST YEAST | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | claimed |
| US-20060003948-A1 | Compositions that include a triterpene and a carrier | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2006-01-05 | — | — | US | disclosed |
| WO-2005077377-A1 | COMPOSITIONS THAT INCLUDE A TRITERPENE AND A CARRIER | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2005-08-25 | — | — | WO | disclosed |
| US-20050014730-A1 | Anti-fungal formulation of triterpene and essential oil | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2005-01-20 | — | — | US | disclosed |
| WO-2004089357-A2 | ANTI-FUNGAL FORMULATION OF TRITERPENE AND ESSENTIAL OIL | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2004-10-21 | — | — | WO | disclosed |
| US-20040097436-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-05-20 | — | — | US | disclosed |
| US-20020119935-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-08-29 | — | — | US | disclosed |
| WO-2002026762-A1 | TRITERPENES HAVING ANTIBACTERIAL ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | disclosed |
| WO-2002026761-A1 | TRITERPENES HAVING FUNGICIDAL ACTIVITY AGAINST YEAST | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | disclosed |
| US-5695909-A | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| US-5665887-A | Methine compound | FUJI PHOTO FILM CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128210-A1 | Triterpenes having human antifungal and antiyeast activity | ERG28, LSS, MANBA | TSHR 4070/4885SLC22A6 3808/4885LMNA 1689/4885 |
| US-20050014730-A1 | Anti-fungal formulation of triterpene and essential oil | BET1, VRK1, VRK2 | TSHR 3878/4885SLC22A6 4841/4885LMNA 3225/4885 |
| US-20040097436-A1 | Triterpenes having antibacterial activity | BET1, PGGT1B, LSS | TSHR 3699/4885SLC22A6 3610/4885LMNA 2543/4885 |
| US-20060003948-A1 | Compositions that include a triterpene and a carrier | PGGT1B, BET1, CYP51A1 | TSHR 4546/4885SLC22A6 785/4885LMNA 1662/4885 |
| US-20020119935-A1 | Triterpenes having antibacterial activity | BET1, PGGT1B, LSS | TSHR 3699/4885SLC22A6 3610/4885LMNA 2543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.