Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CBFB | Q13951 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | CIT | O14578 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.45 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.45 |
| ▸ | BUB1 | O43683 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409107 | 0.92 | AR (0.47) | ARCBFBTGFBR1JAK2CYP1A1 | |
| SCHEMBL5956473 | 0.88 | TGFBR1 (0.48) | TGFBR1JAK2CDC7PLK4CIT | |
| SCHEMBL5956486 | 0.82 | TGFBR1 (0.57) | TGFBR1JAK2CDC7PLK4CIT | |
| SCHEMBL5956553 | 0.77 | TGFBR1 (0.61) | TGFBR1KDR | |
| SCHEMBL5956435 | 0.76 | TGFBR1 (0.48) | TGFBR1JAK2EGFRFLT1JAK1 | |
| SCHEMBL5695773 | 0.75 | CD274 (0.58) | TGFBR1CYP1A2RIPK2PRKD3ACVR1B | |
| SCHEMBL5956861 | 0.74 | HPGD (0.51) | TGFBR1CCNT1ABL1CDK1BCR | |
| SCHEMBL28707194 | 0.74 | CYP1A2 (0.57) | ARCYP1A1CYP1A2CYP1B1MAPT | |
| SCHEMBL6181678 | 0.73 | TGFBR1 (0.48) | ARCBFBTGFBR1JAK2CYP1A1 | |
| SCHEMBL6224276 | 0.73 | AHR (0.44) | CBFBTGFBR1JAK2CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004051-A1 | Compounds | DODIC NERINA | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004051-A1 | Compounds | SMAD3, SMAD2, TGFBR1 | AR 363/4885CBFB 1767/4885TGFBR1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.