Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.46 |
| ▸ | CIT | O14578 | 3/20 | 0.46 |
| ▸ | GSK3B | P49841 | 3/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 2/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.46 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.46 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956758 | 1.00 | ROCK2 (0.46) | ROCK2ROCK1CITGSK3BPRKD3 | |
| SCHEMBL4442264 | 0.91 | ROCK2 (0.48) | ROCK2ROCK1CITGSK3BPRKD3 | |
| SCHEMBL4442306 | 0.91 | ROCK2 (0.48) | ROCK2ROCK1CITGSK3BPRKD3 | |
| SCHEMBL4442272 | 0.91 | ROCK2 (0.48) | ROCK2ROCK1CITGSK3BPRKD3 | |
| SCHEMBL5140157 | 0.89 | JAK2 (0.49) | ROCK2ROCK1CITGSK3BPRKD3 | |
| SCHEMBL5140162 | 0.89 | JAK2 (0.49) | ROCK2ROCK1CITGSK3BPRKD3 | |
| SCHEMBL4443531 | 0.86 | PAK1 (0.35) | GSK3B | |
| SCHEMBL4443519 | 0.86 | PAK1 (0.35) | GSK3B | |
| SCHEMBL4443791 | 0.86 | PAK1 (0.35) | GSK3B | |
| SCHEMBL2855653 | 0.86 | ROCK2 (0.51) | ROCK2ROCK1CITGSK3BPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270570-B1 | AMIDE COMPOUNDS AND USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2006-05-31 | — | — | EP | claimed |