Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956824 | 0.83 | MEN1 (0.38) | CA2ALDH1A1CASP1SMN1; SMN2KMT2A | |
| SCHEMBL5956637 | 0.83 | MEN1 (0.38) | CA2ALDH1A1CASP1SMN1; SMN2KMT2A | |
| SCHEMBL5956617 | 0.73 | NFKB1 (0.37) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL5956623 | 0.73 | NFKB1 (0.37) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL5956620 | 0.70 | ALDH1A1 (0.44) | ALDH1A1TSHRLMNACTSBGAA | |
| SCHEMBL5956616 | 0.70 | ALDH1A1 (0.44) | ALDH1A1TSHRLMNACTSBGAA | |
| SCHEMBL5956849 | 0.70 | KMT2A (0.41) | CA2ALDH1A1CASP1KMT2AMEN1 | |
| SCHEMBL5956628 | 0.68 | KMT2A (0.38) | ALDH1A1CASP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5956889 | 0.68 | KMT2A (0.38) | ALDH1A1CASP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9698398 | 0.67 | ALDH1A1 (0.48) | CA2ALDH1A1TP53TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270570-B1 | AMIDE COMPOUNDS AND USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2006-05-31 | — | — | EP | disclosed |