Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76101 | 0.90 | F10 (0.64) | F10 | |
| SCHEMBL76102 | 0.90 | F10 (0.64) | F10 | |
| SCHEMBL5956859 | 0.89 | F10 (0.57) | F10TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL5956961 | 0.88 | F10 (0.64) | F10MTOR | |
| SCHEMBL5956904 | 0.85 | F10 (0.56) | F10MTOR | |
| SCHEMBL5956932 | 0.84 | F10 (0.58) | F10MTOR | |
| SCHEMBL5956894 | 0.84 | F10 (0.58) | F10MTOR | |
| SCHEMBL5956910 | 0.83 | F10 (0.67) | F10MTOR | |
| SCHEMBL5956864 | 0.83 | MEN1 (0.52) | F10TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL5956912 | 0.82 | F10 (0.54) | F10MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633346-B1 | PYRROLIDIN-1, 2- DICARBOXYLIC ACID- 1- (4- ETHINYL- PHENYL) - AMID|- 2- (PHENYL)- AMID| DERIVATIVE AS INHIBITORS OF COAGULATION FACTOR XA AND VIIA FOR THE TREATMENT OF THROMBOSIS | MERCK PATENT GMBH (DE) | 2006-08-23 | — | — | EP | claimed |