⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14408036 | 0.97 | BRD4 (0.33) | — | |
| SCHEMBL20052459 | 0.87 | BRD4 (0.32) | — | |
| SCHEMBL16885241 | 0.72 | BRD4 (0.40) | — | |
| SCHEMBL24116508 | 0.72 | — | — | |
| SCHEMBL28541723 | 0.72 | HTT (0.36) | — | |
| SCHEMBL9015275 | 0.71 | MAPT (0.43) | — | |
| SCHEMBL14973709 | 0.70 | — | — | |
| SCHEMBL14553369 | 0.69 | BRD4 (0.33) | — | |
| SCHEMBL4495595 | 0.69 | LMNA (0.33) | — | |
| SCHEMBL1604494 | 0.69 | RAB9A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107636043-B | Method for producing polyether carbonate polyols | 科思创德国股份有限公司 | 2020-11-20 | — | — | CN | disclosed |
| US-20060063783-A1 | Sulphonylpiperidine derivatives containing an alkenyl or alkynyl moiety for use as matrix metalloproteinase inhibitors | ASTRAZENECA AB (GB) | 2006-03-23 | — | — | US | disclosed |
| EP-1531821-A2 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ALKENYL OR ALKYNYL MOIETY FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | Astrazeneca AB (SE) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004006927-A2 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ALKENYL OR ALKYNLY MOIETY FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-01-22 | — | — | WO | disclosed |