SCHEMBL5959980

SCHEMBL5959980

CCCCCCC/C=C\CCCCCSCC(=O)OCC(COC(=O)CSCCCCC/C=C\CCCCCCC)OC(=O)CSCCCCC/C=C\CCCCCCC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 3/20 0.57
PRKCE Q02156 2/20 0.57
PRKCQ Q04759 2/20 0.57
PRKCD Q05655 2/20 0.57
ALDH1A1 P00352 2/20 0.51
LMNA P02545 1/20 0.51
ENPP2 Q13822 2/20 0.47
DGKA P23743 1/20 0.47
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
LPAR3 Q9UBY5 1/20 0.46
SELP P16109 1/20 0.46
FAAH O00519 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45
CNR1 P21554 1/20 0.45
CNR2 P34972 1/20 0.45
LPAR1 Q92633 1/20 0.45
DAGLA Q9Y4D2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5944349 0.94 PRKCA (0.67) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL5959954 0.92 PRKCA (0.50) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL14178795 0.92 ALDH1A1 (0.59) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL6026492 0.92 ALDH1A1 (0.59) PRKCAPRKCEPRKCQPRKCDALDH1A1
Tritetradecylthioacetyl Glycerol SCHEMBL4815254 0.92 ALDH1A1 (0.59) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL5944344 0.91 PRKCA (0.63) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL4813894 0.89 PRKCA (0.61) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL13453822 0.87 SELP (0.55) ENPP2RECQLBLMTDP1LPAR3
SCHEMBL4812404 0.86 ALDH1A1 (0.70) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL14178793 0.86 ALDH1A1 (0.54) PRKCAPRKCEPRKCQPRKCDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178713-B2 Sulfur-containing phospholipid derivatives Pronovo Biopharma Norge AS (NO) 2012-05-15 US disclosed
US-8178713-B2 Sulfur-containing phospholipid derivatives Pronovo Biopharma Norge AS (NO) 2012-05-15 US disclosed