Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 12/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960129 | 0.84 | ALOX5 (0.35) | ALOX5 | |
| SCHEMBL2975435 | 0.63 | ALOX5 (0.51) | ALOX5MLYCD | |
| SCHEMBL2981087 | 0.63 | ALOX5 (0.58) | ALOX5MLYCD | |
| SCHEMBL5586496 | 0.61 | PIM1 (0.35) | ALOX5 | |
| SCHEMBL2989905 | 0.61 | ALOX5 (0.39) | ALOX5MLYCD | |
| SCHEMBL5960212 | 0.60 | MLYCD (0.36) | MLYCD | |
| SCHEMBL2979312 | 0.59 | ALOX5 (0.41) | ALOX5MLYCD | |
| SCHEMBL2989755 | 0.59 | MLYCD (0.51) | ALOX5MLYCD | |
| SCHEMBL5005164 | 0.58 | MIF (0.42) | SCN9AMLYCDPTGS1PTGS2 | |
| SCHEMBL7810674 | 0.54 | ALOX5 (0.51) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636222-A1 | 7-[(1,3-THIAZOL-2-YL)THIO]-COUMARIN DERIVATIVES AND THEIR USE AS LEUKOTRIENE BIOSYNTHESIS INHIBITORS | Merck Frosst Canada Ltd. (CA) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004108720-A1 | 7- (1, 3-THIAZOL-2-YL)THIO!-COUMARIN DERIVATIVES AND THEIR USE AS LEUKOTRIENE BIOSYNTHESIS INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2004-12-16 | — | — | WO | disclosed |