SCHEMBL596041

SCHEMBL596041

[O]C(=O)c1ccccc1C(=O)O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.78
ALOX15 P16050 1/20 0.78
AKR1C3 P42330 3/20 0.58
KDM4E B2RXH2 1/20 0.56
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
HMGB1 P09429 1/20 0.56
HPGD P15428 1/20 0.56
CA4 P22748 1/20 0.56
CA6 P23280 1/20 0.56
CA7 P43166 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CA9 Q16790 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
CA14 Q9ULX7 1/20 0.56
MAPT P10636 2/20 0.54
HDAC8 Q9BY41 1/20 0.54
POLB P06746 1/20 0.52
CDC25B P30305 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL10456304 0.91 ALDH1A1 (0.93) ALDH1A1ALOX15AKR1C3KDM4ECA12
Phthalic Acid SCHEMBL1683321 0.91 ALDH1A1 (0.93) ALDH1A1ALOX15AKR1C3KDM4ECA12
Phthalic Acid SCHEMBL16507585 0.91 ALDH1A1 (0.93) ALDH1A1ALOX15AKR1C3KDM4ECA12
Phthalic Acid SCHEMBL10385601 0.88 ALDH1A1 (0.88) ALDH1A1ALOX15AKR1C3KDM4ECA12
SCHEMBL4652941 0.88 ALDH1A1 (0.56) ALDH1A1ALOX15AKR1C3KDM4ECA12
Phthalic Acid SCHEMBL5668586 0.88 ALDH1A1 (1.00) ALDH1A1ALOX15AKR1C3KDM4ECA12
Phthalic Acid SCHEMBL146125 0.88 ALDH1A1 (1.00) ALDH1A1ALOX15AKR1C3KDM4ECA12
Phthalic Acid SCHEMBL1332278 0.88 ALDH1A1 (1.00) ALDH1A1ALOX15AKR1C3KDM4ECA12
Phthalic Acid SCHEMBL10477086 0.88 ALDH1A1 (1.00) ALDH1A1ALOX15AKR1C3KDM4ECA12
Phthalic Acid SCHEMBL1686043 0.88 ALDH1A1 (1.00) ALDH1A1ALOX15AKR1C3KDM4ECA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103059088-A Dammarane saponin derivatives with novel structure as well as preparation method and anti-microbial application thereof UNIV YANTAI 2013-04-24 CN claimed
CN-102924556-A (20S, 24R)-ocotillol type ginsenoside derivative having antibacterial activity and preparation method and application thereof UNIV YANTAI 2013-02-13 CN claimed
CN-102875628-A (20S,24S)-ocotillol ginsenoside derivatives with antibacterial activity, and preparation method and application thereof UNIV CHINA PHARMA 2013-01-16 CN claimed
EP-0048954-B1 BETA-LACTAM COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND INTERMEDIATE PRODUCTS FOR THE PREPARATION THEREOF SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-12-30 EP claimed
US-4160020-A CELLULOSE ESTERS, CELLULOSE ETHERS ALZA CORPORATION (US) 1979-07-03 US claimed
CN-112898431-B Humanized anti-kallikrein-2 antibodies 弗雷达克斯有限责任公司 2024-05-28 CN disclosed
EP-3567058-B1 HYPROMELLOSE PHTHALATE AND METHOD FOR PRODUCING THE SAME SHINETSU CHEMICAL CO (JP) 2023-09-20 EP disclosed
CN-108136013-B Antibody polypeptides and uses thereof 弗雷达克斯有限责任公司 2023-04-18 CN disclosed
CN-112940432-B Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2022-12-30 CN disclosed
CN-110467681-B Hydroxypropyl methylcellulose phthalate and preparation method thereof 信越化学工业株式会社 2022-04-05 CN disclosed
CN-107074946-B Novel antibodies and uses thereof 坎塔吉亚有限责任公司 2022-03-22 CN disclosed
US-11110038-B2 Dental polymerizable monomers, compositions, adhesive dental materials and kits MITSUI CHEMICALS, INC. (JP) 2021-09-07 US disclosed
US-4145418-A THIENOPYRIDINE SUBSTITUTED CEPHALOSPORINS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1979-03-20 US disclosed
US-4132789-A 7-[2-(2-Imino-4-thiazolin-4-yl)-2-sulfoacetamido]cephalosporins and antibacterial compositions containing them TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1979-01-02 US disclosed
US-4116241-A FOR CONTROLLED ORAL ADMINISTRATION OF DRUG ALZA CORPORATION (US) 1978-09-26 US disclosed
US-4098888-A THIAZOLYLACETAMIDO CEPHALOSPORIN TYPE COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1978-07-04 US disclosed
US-4077407-A POLYSACCHARIDES ALZA CORPORATION (US) 1978-03-07 US disclosed
US-4058122-A Osmotic system with laminated wall formed of different materials ALZA CORPORATION (US) 1977-11-15 US disclosed
US-4014334-A Laminated osmotic system for dispensing beneficial agent ALZA CORPORATION (US) 1977-03-29 US disclosed
US-4008719-A Osmotic system having laminar arrangement for programming delivery of active agent ALZA CORPORATION (US) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11110038-B2 Dental polymerizable monomers, compositions, adhesive dental materials and kits ACTN1, SMCHD1, CAPZA1 ALDH1A1 302/4885ALOX15 1142/4885AKR1C3 3695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.