SCHEMBL5960487

SCHEMBL5960487

CS(=O)(=O)n1cnc2ncnc-2c1N

nearest known ligand 0.30

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
TSHR P16473 1/20 0.30
KMT2A Q03164 1/20 0.30
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1914 0.72 ADORA2A (0.41)
SCHEMBL8044270 0.69
SCHEMBL1276952 0.68 ADORA2A (0.46)
SCHEMBL9149409 0.63 ADORA2B (0.34)
SCHEMBL15030464 0.59 PDE4A (0.35) TSHRPDE4APDE4BPDE4CPDE4D
SCHEMBL19848667 0.58 DDB1 (0.41) TSHRKMT2A
SCHEMBL19911413 0.58 MAPT (0.49) TSHRKMT2A
SCHEMBL2115745 0.57 ADORA2A (0.33)
SCHEMBL24668538 0.56 HDAC6 (0.38) PDE4APDE4BPDE4CPDE4D
SCHEMBL28708847 0.56 LTA4H (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1660119-A2 MULTI-ANTIGEN VECTORS FOR MELANOMA Sanofi Pasteur Limited (CA) 2006-05-31 EP disclosed
WO-2005026370-A2 MULTI-ANTIGEN VECTORS FOR MELANOMA SANOFI PASTEUR LIMTED. (CA) 2005-03-24 WO disclosed