Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2687635 | 0.90 | GABRA5 (0.54) | GABRA5 | |
| SCHEMBL10193063 | 0.88 | GABRA5 (0.62) | GABRA5GABRA1 | |
| SCHEMBL2689395 | 0.86 | GABRA5 (0.64) | GABRA5 | |
| SCHEMBL2687714 | 0.83 | GABRA5 (0.62) | GABRA5 | |
| SCHEMBL5959767 | 0.83 | CYP2D6 (0.46) | GABRA5GABRA1 | |
| SCHEMBL2688087 | 0.82 | GABRA5 (0.63) | GABRA5 | |
| SCHEMBL5960542 | 0.81 | ABCB11 (0.40) | GABRA5 | |
| SCHEMBL2688333 | 0.80 | GABRA5 (0.63) | GABRA5GABRA1 | |
| SCHEMBL2688356 | 0.77 | GABRA5 (0.61) | GABRA5 | |
| SCHEMBL2688726 | 0.76 | GABRA5 (0.60) | GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062687-A1 | TRIAZOLE DERIVATIVES AND THEIR USE FOR NEUROLOGICAL DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-05-18 | — | — | WO | disclosed |