SCHEMBL5960773

SCHEMBL5960773

CC[Si](CC)(CC)OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.33
CA2 P00918 4/20 0.33
F2 P00734 2/20 0.33
PRSS1 P07477 2/20 0.33
PRSS2 P07478 2/20 0.33
PRSS3 P35030 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5960799 0.94 F2 (0.39) CA1CA2F2PRSS1PRSS2
SCHEMBL5960761 0.92 F2 (0.40) CA1CA2F2PRSS1PRSS2
SCHEMBL5960745 0.92 F2 (0.40) CA1CA2F2PRSS1PRSS2
SCHEMBL5960795 0.92 F2 (0.40) CA1CA2F2PRSS1PRSS2
SCHEMBL5960815 0.92 F2 (0.40) CA1CA2F2PRSS1PRSS2
SCHEMBL5960760 0.92 F2 (0.40) CA1CA2F2PRSS1PRSS2
SCHEMBL5960759 0.92 F2 (0.40) CA1CA2F2PRSS1PRSS2
SCHEMBL5960801 0.88
SCHEMBL36993 0.79 CA1 (0.30) CA1CA2
SCHEMBL5960742 0.77 CA2 (0.32) CA1CA2F2PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1688423-A1 Silylation of hydroxyl group-containing compounds Shin-Etsu Chemical Co., Ltd. (JP) 2006-08-09 EP disclosed
EP-1334975-B1 Silylation of hydroxyl group-containing compounds SHINETSU CHEMICAL CO (JP) 2006-07-12 EP disclosed
US-6875880-B2 Silylation of hydroxyl groups SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-04-05 US disclosed
EP-1334975-A1 Silylation of hydroxyl group-containing compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-08-13 EP disclosed
US-20030139619-A1 Silylation of hydroxyl groups SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-07-24 US disclosed