Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 11/20 | 0.39 |
| ▸ | CA1 | P00915 | 10/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960759 | 1.00 | F2 (0.40) | F2PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL5960761 | 1.00 | F2 (0.40) | F2PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL5960760 | 1.00 | F2 (0.40) | F2PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL5960745 | 1.00 | F2 (0.40) | F2PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL5960815 | 1.00 | F2 (0.40) | F2PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL5960799 | 0.98 | F2 (0.39) | F2PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL5960773 | 0.92 | CA1 (0.33) | F2PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL5960801 | 0.84 | — | — | |
| SCHEMBL5960736 | 0.79 | CA2 (0.43) | F2PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL5960743 | 0.79 | CA2 (0.43) | F2PRSS1PRSS2PRSS3CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1688423-A1 | Silylation of hydroxyl group-containing compounds | Shin-Etsu Chemical Co., Ltd. (JP) | 2006-08-09 | — | — | EP | disclosed |
| EP-1334975-B1 | Silylation of hydroxyl group-containing compounds | SHINETSU CHEMICAL CO (JP) | 2006-07-12 | — | — | EP | disclosed |
| US-6875880-B2 | Silylation of hydroxyl groups | SHIN-ETSU CHEMICAL, CO., LTD. (JP) | 2005-04-05 | — | — | US | disclosed |
| EP-1334975-A1 | Silylation of hydroxyl group-containing compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-20030139619-A1 | Silylation of hydroxyl groups | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-07-24 | — | — | US | disclosed |