Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.52 |
| ▸ | FNTA | P49354 | 5/20 | 0.51 |
| ▸ | FNTB | P49356 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4373341 | 0.82 | FNTA (0.46) | RORCFNTAFNTB | |
| SCHEMBL4370247 | 0.82 | FNTA (0.47) | RORCFNTAFNTB | |
| SCHEMBL4381109 | 0.78 | FNTA (0.54) | RORCFNTAFNTB | |
| SCHEMBL4381517 | 0.77 | FNTA (0.50) | FNTAFNTB | |
| SCHEMBL4052433 | 0.75 | RORC (0.55) | RORCFNTAFNTB | |
| SCHEMBL5776979 | 0.71 | RORC (0.63) | RORCFNTAFNTB | |
| SCHEMBL5781212 | 0.71 | FNTA (0.67) | RORCFNTAFNTB | |
| SCHEMBL5549507 | 0.69 | RORC (0.47) | RORCFNTAFNTB | |
| SCHEMBL6586870 | 0.69 | FNTA (0.77) | RORCFNTAFNTB | |
| SCHEMBL5783176 | 0.69 | FNTA (0.69) | RORCFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153958-B2 | Farnesyl transferase inhibiting benzoheterocyclic derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-12-26 | — | — | US | disclosed |
| US-20040034218-A1 | Farnesyl transferase inhibiting benzoheterocyclic derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034218-A1 | Farnesyl transferase inhibiting benzoheterocyclic derivatives | FNTA, FNTB, RCE1 | RORC 209/4885FNTA 1/4885FNTB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.