Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15030939 | 0.88 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8745342 | 0.88 | ZDHHC7 (0.41) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL4380443 | 0.85 | MGAM (0.34) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL4972104 | 0.85 | MGAM (0.34) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL4375843 | 0.85 | MGAM (0.34) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL4377130 | 0.85 | MGAM (0.34) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL12385422 | 0.85 | GAA (0.43) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1325863 | 0.84 | L3MBTL1 (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8379492 | 0.83 | GAA (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL17759227 | 0.83 | TSHR (0.34) | GAAMGAMSIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466297-B2 | Manufacturing process for (S)-Pregabalin | SOUKUP MILAN (US) | 2013-06-18 | — | — | US | disclosed |
| US-20120123134-A1 | Manufacturing process for (S)-Pregabalin | Drug Process Licensing Associates LLC (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123134-A1 | Manufacturing process for (S)-Pregabalin | GABRE, GABRP, GABBR1 | GAA 628/4885MGAM 2461/4885SI 1092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.