SCHEMBL5961754

SCHEMBL5961754

CCN(O)[C@@H](CCS)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.36
CHRM1 P11229 1/20 0.33
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ANPEP P15144 1/20 0.32
ENPEP Q07075 1/20 0.32
GRIK1 P39086 1/20 0.31
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
GRIK2 Q13002 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL313183 1.00 FOLH1 (0.36) FOLH1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL898887 0.83 PTGS1 (0.36) FOLH1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL313272 0.83 PTGS1 (0.36) FOLH1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL4655463 0.79 CYP1A2 (0.45) FOLH1HDAC1HDAC2GRIK1SLC1A3
SCHEMBL7701636 0.79 CYP1A2 (0.45) FOLH1HDAC1HDAC2GRIK1SLC1A3
SCHEMBL3728136 0.78 CHRM1 (0.33) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL1221384 0.76 ALOX15 (0.45) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL3335954 0.76 ALOX15 (0.45) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL7280578 0.76 FOLH1 (0.40) FOLH1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL28243274 0.75 FOLH1 (0.33) FOLH1CHRM1AKR1A1CHRM3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1002075-B1 ADIPOCYTE-SPECIFIC PROTEIN HOMOLOGS ZYMOGENETICS INC (US) 2006-05-24 EP disclosed
US-20060040360-A1 Adipocyte complement related protein homolog zacrp7 ZYMOGENETICS, INC. (US) 2006-02-23 US disclosed
US-20050043243-A1 Adipocyte-specific protein homologs SHEPPARD PAUL O (US) 2005-02-24 US disclosed
US-20050042719-A1 Adipocyte complement related protein homolog zacrp5 ZYMOGENETICS, INC. 2005-02-24 US disclosed
US-6803450-B2 FUSION PROTEIN; GENETIC ENGINEERING; ENERGY STORAGE ZYMOGENETICS, INC. 2004-10-12 US disclosed
US-20030176659-A1 Adipocyte-specific protein homologs ZYMOGENETICS, INC. 2003-09-18 US disclosed
US-20030176658-A1 Adipocyte-specific protein homologs ZYMOGENETICS, INC. 2003-09-18 US disclosed
US-20030129698-A1 Adipocyte complement related protein homolog zacrp7 ZYMOGENETICS, INC. 2003-07-10 US disclosed
US-6566499-B1 Polypeptide for use in the treatment of energy balance defects ZYMOGENETICS, INC. 2003-05-20 US disclosed
US-6518403-B2 Polypeptide for use in the diagnosis and treatment of glycogen storage defects SHEPPARD PAUL O (US) 2003-02-11 US disclosed
US-20020156243-A1 Adipocyte-specific protein homologs ZYMOGENETICS, INC. 2002-10-24 US disclosed
EP-1185645-A1 ADIPOCYTE COMPLEMENT RELATED PROTEIN HOMOLOG ZACRP7 ZymoGenetics, Inc. (US) 2002-03-13 EP disclosed
EP-1185643-A1 ADIPOCYTE COMPLEMENT RELATED PROTEIN HOMOLOG ZACRP5 ZymoGenetics, Inc. (US) 2002-03-13 EP disclosed
US-6265544-B1 NUCLEOTIDE SEQUENCE CODING ADIPOSE POLYPEPTIDE; FOR THE DETECTION OF MODULATORS OF ADIPOSE SECRETORY PATHWAYS ZYMOGENETICS, INC. 2001-07-24 US disclosed
WO-2000073448-A1 ADIPOCYTE COMPLEMENT RELATED PROTEIN HOMOLOG ZACRP7 ZYMOGENETICS, INC. (US) 2000-12-07 WO disclosed
WO-2000073444-A1 ADIPOCYTE COMPLEMENT RELATED PROTEIN HOMOLOG ZACRP5 ZYMOGENETICS, INC. (US) 2000-12-07 WO disclosed
EP-1002075-A1 ADIPOCYTE-SPECIFIC PROTEIN HOMOLOGS ZymoGenetics, Inc. (US) 2000-05-24 EP disclosed
WO-1999004000-A1 ADIPOCYTE-SPECIFIC PROTEIN HOMOLOGS ZYMOGENETICS, INC. (US) 1999-01-28 WO disclosed