Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12600555 | 0.87 | CYP3A4 (0.47) | MAOBRELAMAPTALDH1A1PTGS2 | |
| SCHEMBL11994860 | 0.84 | MAOB (0.50) | MAOBRELATAS1R3TAS1R1NPC1 | |
| SCHEMBL14041530 | 0.75 | MAOB (0.62) | MAOBRELANPC1RAB9AMAPT | |
| SCHEMBL13476090 | 0.72 | RELA (0.58) | MAOBRELATAS1R3TAS1R1NPC1 | |
| SCHEMBL16489730 | 0.71 | RELA (0.61) | MAOBRELANPC1RAB9AMAPT | |
| SCHEMBL14665948 | 0.71 | RELA (0.61) | MAOBRELANPC1RAB9AMAPT | |
| SCHEMBL12376972 | 0.71 | RELA (0.61) | MAOBRELANPC1RAB9AMAPT | |
| SCHEMBL10623831 | 0.71 | RELA (0.83) | MAOBRELANPC1RAB9AMAPT | |
| SCHEMBL10623834 | 0.71 | RELA (0.83) | MAOBRELANPC1RAB9AMAPT | |
| SCHEMBL92159 | 0.71 | NQO1 (0.78) | MAOBRELASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168734-B2 | Lateral alpha-substituted acrylate compound and polymer thereof | JNC CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |