SCHEMBL5961798

SCHEMBL5961798

Cc1cc(OC(=O)C2CCC(C3CCC(C)CC3)CC2)cc(C)c1C

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ATM Q13315 1/20 0.39
ELANE P08246 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
POLB P06746 2/20 0.36
MAP2K1 Q02750 1/20 0.35
TP53 P04637 1/20 0.35
ALOX15 P16050 1/20 0.35
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
EPHX2 P34913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5961803 0.95 KMT2A (0.44) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL12718792 0.85 TDP1 (0.39) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL20152450 0.85 ALDH1A1 (0.39) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL20152470 0.83 KMT2A (0.42) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL20276018 0.83 KMT2A (0.42) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL19431498 0.83 KMT2A (0.44) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL815871 0.82 KMT2A (0.36) KMT2AHTTSMN1; SMN2TDP1L3MBTL1
SCHEMBL25500845 0.82 KMT2A (0.61) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL22432168 0.81 KMT2A (0.46) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL2741529 0.81 KMT2A (0.40) KMT2AHTTSMN1; SMN2TDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168734-B2 Lateral alpha-substituted acrylate compound and polymer thereof JNC CORPORATION (JP) 2012-05-01 US disclosed
US-7662443-B2 Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2010-02-16 US disclosed
US-20080121843-A1 Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices HECKMEIER MICHAEL 2008-05-29 US disclosed
US-7303791-B2 Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices MERCK PATENT GMBH (DE) 2007-12-04 US disclosed
US-7157124-B2 Polymerizable compounds and their polymers CHISSO PETROCHEMICAL CORPORATION (JP) 2007-01-02 US disclosed