SCHEMBL5961803

SCHEMBL5961803

Cc1cc(OC(=O)C2CCC(C)CC2)cc(C)c1C

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ATM Q13315 1/20 0.41
ELANE P08246 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
POLB P06746 1/20 0.39
MAP2K1 Q02750 1/20 0.37
TP53 P04637 1/20 0.37
ALOX15 P16050 1/20 0.37
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5961798 0.95 KMT2A (0.41) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL20276018 0.87 KMT2A (0.42) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL20152470 0.87 KMT2A (0.42) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL19431498 0.87 KMT2A (0.44) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL22432168 0.85 KMT2A (0.46) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL20152466 0.83 ALDH1A1 (0.41) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL13135288 0.83 KMT2A (0.49) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL18636252 0.81 KMT2A (0.47) KMT2AHTTSMN1; SMN2TDP1ATM
SCHEMBL815637 0.81 KMT2A (0.39) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL13135270 0.80 KMT2A (0.68) KMT2AHTTSMN1; SMN2TDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168734-B2 Lateral alpha-substituted acrylate compound and polymer thereof JNC CORPORATION (JP) 2012-05-01 US disclosed
US-7157124-B2 Polymerizable compounds and their polymers CHISSO PETROCHEMICAL CORPORATION (JP) 2007-01-02 US disclosed