Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696057 | 0.91 | PARP10 (0.45) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL7666233 | 0.85 | NQO1 (0.64) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL10681956 | 0.82 | MAPT (0.46) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL19220415 | 0.78 | LTA4H (0.57) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL10685576 | 0.78 | NPC1 (0.57) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL10685241 | 0.76 | KDM4E (0.47) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL9312577 | 0.75 | NQO1 (0.61) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL8924890 | 0.74 | MEN1 (0.58) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL10878020 | 0.74 | PARP10 (0.56) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL18911078 | 0.73 | NQO1 (0.58) | NQO1PARP10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168734-B2 | Lateral alpha-substituted acrylate compound and polymer thereof | JNC CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |