Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961802 | 0.91 | NQO1 (0.50) | PARP10PRSS1PRSS2PRSS3TDP1 | |
| SCHEMBL10692941 | 0.83 | GAA (0.42) | PARP10PRSS1PRSS2PRSS3TDP1 | |
| SCHEMBL28021522 | 0.77 | MAPT (0.51) | PARP10PRSS1PRSS2PRSS3TDP1 | |
| SCHEMBL7666233 | 0.77 | NQO1 (0.64) | PARP10PRSS1PRSS2PRSS3TDP1 | |
| SCHEMBL5690948 | 0.76 | KMT2A (0.39) | TSHRALDH1A1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL10681956 | 0.75 | MAPT (0.46) | PARP10PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL19220415 | 0.71 | LTA4H (0.57) | PARP10PRSS1PRSS2PRSS3NQO1 | |
| SCHEMBL10685576 | 0.71 | NPC1 (0.57) | PARP10PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL19036538 | 0.70 | PARP10 (0.66) | PARP10PRSS1PRSS2PRSS3TDP1 | |
| SCHEMBL10685241 | 0.69 | KDM4E (0.47) | PARP10PRSS1PRSS2PRSS3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257591-A2 | Process for preparing diphenylalkene derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |