Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29782139 | 0.79 | HPGD (0.48) | HPGDTSHRMAPTNPC1RAB9A | |
| SCHEMBL2651614 | 0.79 | HPGD (0.48) | HPGDTSHRMAPTNPC1RAB9A | |
| SCHEMBL2647013 | 0.73 | HPGD (0.54) | HPGDTSHRMAPTNPC1RAB9A | |
| SCHEMBL31620801 | 0.73 | MAPT (0.47) | HPGDMAPTNPC1RAB9AMEN1 | |
| SCHEMBL19309852 | 0.70 | HPGD (0.51) | HPGDTSHRMAPTNPC1RAB9A | |
| SCHEMBL4000183 | 0.70 | TSHR (0.48) | HPGDTSHRMAPTKDM4EHTT | |
| SCHEMBL25107589 | 0.70 | MAPT (0.50) | HPGDTSHRMAPTNPC1RAB9A | |
| SCHEMBL28731822 | 0.70 | KDM4E (0.49) | HPGDMAPTNPC1RAB9AMEN1 | |
| SCHEMBL1299471 | 0.70 | KCNQ3 (0.44) | HPGDMAPTRAB9AMEN1KMT2A | |
| SCHEMBL7828899 | 0.69 | TSHR (0.63) | HPGDTSHRMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109343-B2 | Metal catalysts and methods for making and using same | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2006-09-19 | — | — | US | disclosed |
| US-20050010049-A1 | Metal catalysts and methods for making and using same | DAVIES HUW M L (US) | 2005-01-13 | — | — | US | disclosed |
| US-6762304-B2 | BIS-TRANSITION METAL CATALYSTS HAVING D2 SYMMETRY | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2004-07-13 | — | — | US | disclosed |
| EP-1173278-B1 | METAL CATALYSTS AND METHODS FOR MAKING AND USING SAME | RES FOUNDATION OFSTATE UNIVERS (US) | 2004-06-30 | — | — | EP | disclosed |
| US-20020183535-A1 | Metal catalysts and methods for making and using same | DAVIES HUW M L (US) | 2002-12-05 | — | — | US | disclosed |
| US-6410746-B1 | ORGANOMETALLIC COMPOUND CONTAINING TRANSITION METAL | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | 2002-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183535-A1 | Metal catalysts and methods for making and using same | COMT, SLC6A3, SLC6A2 | HPGD 3992/4885TSHR 101/4885MAPT 2849/4885 |
| US-20050010049-A1 | Metal catalysts and methods for making and using same | SLC6A3, COMT, DRD4 | HPGD 3866/4885TSHR 112/4885MAPT 1443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.