Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12562387 | 0.89 | TSHR (0.50) | TSHRALDH1A1AOC3MEN1HTT | |
| SCHEMBL3161510 | 0.88 | MAOB (0.52) | TSHRALDH1A1AOC3MEN1HTT | |
| SCHEMBL16889019 | 0.87 | ALDH1A1 (0.46) | TSHRALDH1A1AOC3MEN1HTT | |
| SCHEMBL13539088 | 0.85 | TSHR (0.45) | TSHRALDH1A1AOC3MEN1HTT | |
| SCHEMBL11708893 | 0.85 | TAAR1 (0.52) | TSHRALDH1A1AOC3MEN1HTT | |
| SCHEMBL14271365 | 0.83 | ALDH1A1 (0.54) | TSHRALDH1A1AOC3MEN1HTT | |
| SCHEMBL17886005 | 0.83 | AOC3 (0.44) | TSHRALDH1A1AOC3MEN1HTT | |
| SCHEMBL1026555 | 0.83 | CARM1 (0.58) | TSHRALDH1A1AOC3MEN1HTT | |
| SCHEMBL15307291 | 0.83 | ALDH1A1 (0.43) | TSHRALDH1A1AOC3MEN1HTT | |
| SCHEMBL251096 | 0.82 | ALDH1A1 (0.42) | TSHRALDH1A1AOC3MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11779912-B2 | Synthesis and characterization of Ru alkylidene complexes | UMICORE AG & CO. KG (DE) | 2023-10-10 | — | — | US | disclosed |
| US-11779912-B2 | Synthesis and characterization of Ru alkylidene complexes | UMICORE AG & CO. KG (DE) | 2023-10-10 | — | — | US | disclosed |
| WO-2022109573-A1 | MACROCYCLES CONTAINING A 1,3,4-OXADIAZOLE RING FOR USE AS MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-05-27 | — | — | WO | disclosed |
| US-20210394167-A1 | SYNTHESIS AND CHARACTERIZATION OF RU ALKYLIDENE COMPLEXES | UMICORE AG & CO. KG (DE) | 2021-12-23 | — | — | US | disclosed |
| US-11185853-B2 | Catalysts for polycarbonate production | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2021-11-30 | — | — | US | disclosed |
| US-11123722-B2 | Synthesis and characterization of Ru alkylidene complexes | UMICORE AG & CO. KG | 2021-09-21 | — | — | US | disclosed |
| US-11059801-B2 | Methods to induce targeted protein degradation through bifunctional molecules | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-07-13 | — | — | US | disclosed |
| EP-3528942-B1 | SYNTHESIS AND CHARACTERIZATION OF RU ALKYLIDENE COMPLEXES | UMICORE AG & CO KG (DE) | 2021-04-28 | — | — | EP | disclosed |
| US-10954330-B2 | Use of specific aminosilyl monomers in the manufacture of rubber | TRINSEO EUROPE GMBH (CH) | 2021-03-23 | — | — | US | disclosed |
| US-20200377636-A1 | Use of Specific Aminosilyl Monomers in the Manufacture of Rubber | SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) | 2020-12-03 | — | — | US | disclosed |
| US-20050131170-A1 | Elastic substantially linear olefin polymers | LAI SHIH-YAW (US) | 2005-06-16 | — | — | US | disclosed |
| EP-1057867-B1 | RESIN DISPERSION, METHOD OF PREPARING THE SAME, RESIN-COATED METAL SHEET OBTAINED WITH THE SAME, AND PROCESS FOR PRODUCING LAMINATE | MITSUI CHEMICALS INC (JP) | 2005-04-20 | — | — | EP | disclosed |
| US-6825369-B1 | TITANIUM COMPLEX COMPRISING MONOCYCLOPENTADIENYL WITH ALKOXY AND/OR ARYLOXY SUBSTITUENTS; OLEFIN POLYMERIZATION CATALYSTS | THE DOW CHEMICAL COMPANY | 2004-11-30 | — | — | US | disclosed |
| US-20040072849-A1 | Dioxanes and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-04-15 | — | — | US | disclosed |
| EP-0783006-B1 | Process for the preparation of ethylene polymers | DOW CHEMICAL CO (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5665800-A | USEFUL IN FIBERS, FILMS, MOLDINGS | THE DOW CHEMICAL COMPANY (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0783006-A2 | Process for the preparation of ethylene polymers | THE DOW CHEMICAL COMPANY (US) | 1997-07-09 | — | — | EP | disclosed |
| EP-0196484-B1 | PRESSURE SENSITIVE MANIFOLD SHEET | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1990-05-09 | — | — | EP | disclosed |
| US-4704379-A | Pressure sensitive manifold sheet | KANZAKI PAPER MANUFACTURING CO. LTD. (JP) | 1987-11-03 | — | — | US | disclosed |
| EP-0196484-A1 | Pressure sensitive manifold sheet | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1986-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210394167-A1 | SYNTHESIS AND CHARACTERIZATION OF RU ALKYLIDENE COMPLEXES | PORCN, ORC3, COASY | TSHR 4008/4885ALDH1A1 1478/4885AOC3 21/4885 |
| US-11059801-B2 | Methods to induce targeted protein degradation through bifunctional molecules | CRBN, XIAP, MDM2 | TSHR 3312/4885ALDH1A1 3984/4885AOC3 3662/4885 |
| US-20040072849-A1 | Dioxanes and uses thereof | UTS2R, HDAC5, AMDHD2 | TSHR 3763/4885ALDH1A1 682/4885AOC3 2471/4885 |
| US-11779912-B2 | Synthesis and characterization of Ru alkylidene complexes | PORCN, ORC3, COASY | TSHR 4008/4885ALDH1A1 1478/4885AOC3 21/4885 |
| US-11123722-B2 | Synthesis and characterization of Ru alkylidene complexes | PORCN, ORC3, COASY | TSHR 4008/4885ALDH1A1 1478/4885AOC3 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.