Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | XPNPEP2 | O43895 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130621 | 0.87 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1KMT2APOLBHSD17B10 | |
| SCHEMBL11130618 | 0.87 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1KMT2APOLBHSD17B10 | |
| SCHEMBL20611377 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KMT2APOLBHSD17B10 | |
| SCHEMBL5964142 | 0.85 | CMA1 (0.48) | SMN1; SMN2ALDH1A1KMT2ALMNANPSR1 | |
| SCHEMBL5964139 | 0.85 | CMA1 (0.48) | SMN1; SMN2ALDH1A1KMT2ALMNANPSR1 | |
| SCHEMBL5963563 | 0.85 | HSD17B10 (0.53) | SMN1; SMN2HSD17B10XPNPEP2ACENPC1 | |
| SCHEMBL3591879 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1KMT2APOLBHSD17B10 | |
| SCHEMBL4473488 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1KMT2APOLBHSD17B10 | |
| SCHEMBL11032344 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1KMT2APOLBHSD17B10 | |
| Tetradecane SCHEMBL27504192 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KMT2APOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122521-B2 | COMPRISING TRIPEPTIDE UNIT OF THE FORMULA (flp-Yaa-Gly)N, WHERE Yaa IS ANY AMINO ACID, FLP IS 4(R)-FLUORO-L-PROLINE, AND N IS AT LEAST 3; INCREASED STABILITY; STRONGER TRIPLE HELIX THAN NATIVE COLLAGEN; FOR USE SUCH AS IN ARTIFICIAL SKIN | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-10-17 | — | — | US | disclosed |
| WO-2005000872-A2 | COLLAGEN MIMICS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2005-01-06 | — | — | WO | disclosed |
| US-20050004032-A1 | Collagen mimics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-01-06 | — | — | US | disclosed |