Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 5/20 | 0.45 |
| ▸ | XPNPEP2 | O43895 | 1/20 | 0.45 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963526 | 0.85 | SMN1; SMN2 (0.51) | HSD17B10SMN1; SMN2ACEXPNPEP2UCHL1 | |
| SCHEMBL2489313 | 0.84 | HSD17B10 (0.71) | HSD17B10SMN1; SMN2ACEUCHL1LMNA | |
| SCHEMBL8395469 | 0.84 | HSD17B10 (0.71) | HSD17B10SMN1; SMN2ACEUCHL1LMNA | |
| SCHEMBL9609459 | 0.84 | HSD17B10 (0.71) | HSD17B10SMN1; SMN2ACEUCHL1LMNA | |
| SCHEMBL38017 | 0.84 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2UCHL1CYP2C19 | |
| SCHEMBL192921 | 0.84 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2UCHL1CYP2C19 | |
| SCHEMBL20811620 | 0.84 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2UCHL1CYP2C19 | |
| SCHEMBL2489604 | 0.84 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2UCHL1CYP2C19 | |
| SCHEMBL641763 | 0.84 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2UCHL1CYP2C19 | |
| SCHEMBL29038999 | 0.84 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2UCHL1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122521-B2 | COMPRISING TRIPEPTIDE UNIT OF THE FORMULA (flp-Yaa-Gly)N, WHERE Yaa IS ANY AMINO ACID, FLP IS 4(R)-FLUORO-L-PROLINE, AND N IS AT LEAST 3; INCREASED STABILITY; STRONGER TRIPLE HELIX THAN NATIVE COLLAGEN; FOR USE SUCH AS IN ARTIFICIAL SKIN | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-10-17 | — | — | US | disclosed |
| US-20050004032-A1 | Collagen mimics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-01-06 | — | — | US | disclosed |