Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004041 | 0.80 | LMNA (0.42) | PDE3APDE4DSLC29A1LMNACACNA1F | |
| SCHEMBL5940639 | 0.76 | PDE3A (0.44) | PDE3APDE4DSLC29A1LMNACACNA1F | |
| SCHEMBL28845396 | 0.76 | PDE3A (0.39) | PDE3APDE4DSLC29A1LMNACACNA1F | |
| SCHEMBL30612759 | 0.70 | PDE3A (0.42) | PDE3APDE4DSLC29A1LMNACACNA1F | |
| SCHEMBL30612741 | 0.69 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNACACNA1F | |
| SCHEMBL30592430 | 0.67 | LMNA (0.46) | PDE3APDE4DSLC29A1LMNACACNA1F | |
| SCHEMBL1739169 | 0.66 | PDE3A (0.32) | PDE3APDE4DSLC29A1LMNACACNA1F | |
| SCHEMBL5903747 | 0.66 | LMNA (0.40) | PDE3APDE4DSLC29A1LMNACACNA1F | |
| SCHEMBL4745588 | 0.66 | PDE3A (0.45) | PDE3APDE4DSLC29A1LMNACACNA1F | |
| SCHEMBL30612748 | 0.66 | PDE3A (0.40) | PDE3APDE4DSLC29A1LMNACACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058686-B1 | 2'-FLUORONUCLEOSIDES | UNIV EMORY (US) | 2006-11-02 | — | — | EP | disclosed |