SCHEMBL5963724

SCHEMBL5963724

Cc1ccc(Cl)c(-c2cc[c]c(C)c2Cl)c1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALKBH3 Q96Q83 1/20 0.34
PDK2 Q15119 1/20 0.33
LRRK2 Q5S007 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4431124 0.79 ELANE (0.36) ALKBH3LRRK2
SCHEMBL7455214 0.78 POLB (0.41) PDK2
SCHEMBL4429962 0.74 ALKBH3 (0.36) ALKBH3
SCHEMBL5086316 0.73 ALKBH3 (0.35) ALKBH3LRRK2
SCHEMBL28015677 0.73 RAPGEF4 (0.35) PDK2
SCHEMBL4439316 0.71 ALKBH3 (0.34) ALKBH3
SCHEMBL4431126 0.71 ALKBH3 (0.37) ALKBH3LRRK2
SCHEMBL5086321 0.70 ALKBH3 (0.36) ALKBH3LRRK2
SCHEMBL3412996 0.70 ALKBH3 (0.36) ALKBH3LRRK2
SCHEMBL11405867 0.70 PDK2 (0.34) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7094723-B2 Catalysts containing at least one heterocyclic ligand for improving the catalysts' performance of olefin polymerization EQUISTAR CHEMICALS LP (US) 2006-08-22 US disclosed