Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 12/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11405867 | 0.76 | PDK2 (0.34) | PDK2 | |
| SCHEMBL5963724 | 0.73 | ALKBH3 (0.34) | PDK2 | |
| SCHEMBL10987049 | 0.72 | RAPGEF4 (0.31) | RAPGEF4 | |
| SCHEMBL9800413 | 0.71 | ALDH1A1 (0.35) | RAPGEF4FFAR4 | |
| SCHEMBL9243350 | 0.71 | — | — | |
| SCHEMBL7469723 | 0.69 | CYP2A6 (0.40) | — | |
| SCHEMBL7455214 | 0.68 | POLB (0.41) | PDK2 | |
| SCHEMBL3618651 | 0.68 | MYC (0.34) | PDK2 | |
| SCHEMBL17514863 | 0.68 | RAPGEF4 (0.32) | RAPGEF4 | |
| SCHEMBL20553843 | 0.67 | RAPGEF4 (0.34) | RAPGEF4PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |