SCHEMBL5966483

SCHEMBL5966483

COC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](CCCNC(N)=N[N+](=O)[O-])NC(=O)C(CCCCc1ccccc1)Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CTSL P07711 2/20 0.43
KISS1R Q969F8 2/20 0.42
BIRC2 Q13490 1/20 0.41
IDE P14735 3/20 0.41
NPY1R P25929 1/20 0.41
NPY4R P50391 1/20 0.41
FCER2 P06734 1/20 0.41
SSTR3 P32745 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5966484 0.90 BIRC2 (0.44) BIRC2SSTR3
SCHEMBL5966598 0.87 NPY4R (0.53) CTSLBIRC2IDENPY1RNPY4R
SCHEMBL5966605 0.87 NPY4R (0.53) CTSLBIRC2IDENPY1RNPY4R
SCHEMBL5966575 0.83 FNTA (0.49) CTSL
SCHEMBL5966480 0.83 BIRC2 (0.41) BIRC2IDEFCER2SSTR3
SCHEMBL5966537 0.81 CTSS (0.53) CTSLKISS1RFCER2
SCHEMBL5966493 0.80 CTSS (0.52) CTSL
SCHEMBL5966592 0.80 SSTR3 (0.47) KISS1RNPY1RNPY4RSSTR3
SCHEMBL5966559 0.78 CTSS (0.53) CTSLKISS1RFCER2
SCHEMBL5966565 0.77 CTSS (0.49) CTSLSSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060128613-A1 Melanocortin receptor ligands THE PROCTER & GAMBLE COMPANY 2006-06-15 US disclosed
EP-1409540-A2 MELANOCORTIN RECEPTOR LIGANDS THE PROCTER & GAMBLE COMPANY (US) 2004-04-21 EP disclosed
WO-2002026774-A2 MELANOCORTIN RECEPTOR LIGANDS THE PROCTER & GAMBLE COMPANY (US) 2002-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128613-A1 Melanocortin receptor ligands MC3R, MC4R, MC1R CTSL 3363/4885KISS1R 83/4885BIRC2 4708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.