SCHEMBL5966484

SCHEMBL5966484

COC(=O)[C@H](CCCNC(N)=N[N+](=O)[O-])NC(=O)C(CCCCc1ccccc1)Cc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BIRC2 Q13490 2/20 0.44
FNTA P49354 3/20 0.43
FNTB P49356 3/20 0.43
PGGT1B P53609 3/20 0.43
SSTR3 P32745 1/20 0.43
MMP1 P03956 2/20 0.42
MMP3 P08254 2/20 0.42
MMP9 P14780 1/20 0.42
F2 P00734 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
BMP1 P13497 2/20 0.40
MMP2 P08253 1/20 0.40
MMP7 P09237 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5966575 0.91 FNTA (0.49) FNTAFNTBPGGT1BMMP1MMP3
SCHEMBL5966483 0.90 CTSL (0.43) BIRC2SSTR3
SCHEMBL5966592 0.86 SSTR3 (0.47) SSTR3BMP1
SCHEMBL5966565 0.83 CTSS (0.49) SSTR3
SCHEMBL5966675 0.80 REN (0.44) SSTR3F2CA1CA2BMP1
SCHEMBL5966526 0.80 F2 (0.42) SSTR3F2
SCHEMBL5966488 0.79 SSTR3 (0.41) BIRC2SSTR3MMP1MMP3MMP9
SCHEMBL5966476 0.79 BIRC2 (0.44) BIRC2SSTR3MMP1MMP3MMP9
SCHEMBL5966597 0.79 GNPAT (0.45) FNTAFNTBPGGT1BMMP1MMP3
SCHEMBL5966622 0.79 GNPAT (0.45) FNTAFNTBPGGT1BMMP1MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060128613-A1 Melanocortin receptor ligands THE PROCTER & GAMBLE COMPANY 2006-06-15 US disclosed
EP-1409540-A2 MELANOCORTIN RECEPTOR LIGANDS THE PROCTER & GAMBLE COMPANY (US) 2004-04-21 EP disclosed
WO-2002026774-A2 MELANOCORTIN RECEPTOR LIGANDS THE PROCTER & GAMBLE COMPANY (US) 2002-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128613-A1 Melanocortin receptor ligands MC3R, MC4R, MC1R BIRC2 4708/4885FNTA 4205/4885FNTB 4184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.