Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | FCER2 | P06734 | 2/20 | 0.51 |
| ▸ | MC4R | P32245 | 5/20 | 0.50 |
| ▸ | MC3R | P41968 | 5/20 | 0.50 |
| ▸ | MC1R | Q01726 | 3/20 | 0.50 |
| ▸ | CTSC | P53634 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | MC5R | P33032 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5557678 | 1.00 | HTR2A (0.57) | HTR2AHTR2CHTR2BNLNOPRD1 | |
| Hydrochloric Acid SCHEMBL5556491 | 0.98 | HTR2A (0.55) | HTR2AHTR2CHTR2BNLNOPRD1 | |
| SCHEMBL24455558 | 0.86 | CSK (0.55) | HTR2AHTR2CHTR2BNLNOPRD1 | |
| SCHEMBL4574838 | 0.84 | HTR2A (0.53) | HTR2AHTR2CHTR2BNLNOPRD1 | |
| SCHEMBL10069405 | 0.84 | HTR2A (0.64) | HTR2AHTR2CHTR2BOPRD1DPP4 | |
| SCHEMBL15745967 | 0.84 | HTR2A (0.64) | HTR2AHTR2CHTR2BOPRD1DPP4 | |
| SCHEMBL17874879 | 0.84 | HTR2A (0.64) | HTR2AHTR2CHTR2BOPRD1DPP4 | |
| SCHEMBL23052853 | 0.83 | OPRD1 (0.62) | HTR2AHTR2CHTR2BNLNOPRD1 | |
| SCHEMBL6019536 | 0.82 | CTSS (0.61) | HTR2AHTR2CHTR2BNLNOPRD1 | |
| SCHEMBL5556869 | 0.82 | OPRD1 (0.61) | HTR2AHTR2CHTR2BNLNOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128613-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2006-06-15 | — | — | US | disclosed |
| EP-1409540-A2 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002026774-A2 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |
| US-5252560-A | Cyclic imide derivatives, compositions and use | GLAXO INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0520573-A1 | Cyclic imide derivatives | GLAXO INC. (US) | 1992-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128613-A1 | Melanocortin receptor ligands | MC3R, MC4R, MC1R | HTR2A 303/4885HTR2C 235/4885HTR2B 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.