Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432794 | 0.84 | SLC7A5 (0.49) | SLC7A5CPA1CA2CA1FNTA | |
| SCHEMBL432795 | 0.84 | SLC7A5 (0.49) | SLC7A5CPA1CA2CA1FNTA | |
| SCHEMBL31480614 | 0.83 | SLC7A5 (0.47) | SLC7A5CPA1CA2CA1FNTA | |
| SCHEMBL31480546 | 0.82 | SLC7A5 (0.50) | SLC7A5CPA1CA2CA1FNTA | |
| SCHEMBL5341495 | 0.82 | SLC7A5 (0.50) | SLC7A5CPA1CA2CA1FNTA | |
| SCHEMBL23610314 | 0.81 | SLC7A5 (0.51) | SLC7A5CA2FNTAFNTBPOLB | |
| SCHEMBL169321 | 0.80 | SLC7A5 (0.55) | SLC7A5CA2FNTAFNTBPOLB | |
| SCHEMBL169322 | 0.80 | SLC7A5 (0.55) | SLC7A5CA2FNTAFNTBPOLB | |
| Methane SCHEMBL17267562 | 0.79 | SLC7A5 (0.53) | SLC7A5CA2FNTAFNTBPOLB | |
| SCHEMBL11053244 | 0.78 | SLC7A5 (0.51) | SLC7A5CA2FNTAFNTBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060198831-A1 | Nitrosylation of protein SH groups and amino acid residues as a therapeutic modality | BRIGHAM AND WOMEN'S HOSPITAL (US) | 2006-09-07 | — | — | US | disclosed |