Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31480546 | 1.00 | SLC7A5 (0.50) | SLC7A5MMP2CPA1TAAR1CA1 | |
| SCHEMBL432794 | 0.84 | SLC7A5 (0.49) | SLC7A5CPA1CA1CA2FNTA | |
| SCHEMBL432795 | 0.84 | SLC7A5 (0.49) | SLC7A5CPA1CA1CA2FNTA | |
| SCHEMBL31480614 | 0.83 | SLC7A5 (0.47) | SLC7A5CPA1CA1CA2FNTA | |
| SCHEMBL5966737 | 0.82 | SLC7A5 (0.46) | SLC7A5CPA1CA1CA2FNTA | |
| SCHEMBL20856984 | 0.80 | FNTA (0.47) | SLC7A5CPA1FNTAFNTBPOLB | |
| SCHEMBL29800397 | 0.79 | SLC7A5 (0.58) | SLC7A5TAAR1CA2SLC6A2POLB | |
| SCHEMBL5352342 | 0.79 | SLC7A5 (0.58) | SLC7A5TAAR1CA2SLC6A2POLB | |
| SCHEMBL8513742 | 0.78 | OPRM1 (0.46) | SLC7A5CPA1FNTAFNTB | |
| SCHEMBL2542276 | 0.75 | SLC7A5 (0.56) | SLC7A5TAAR1CA2SLC6A2FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005124338-A1 | METHODS OF DETECTING NITROTYROSINE AND AMINOTYROSINE RESIDUES OF PEPTIDES AND PROTEINS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2005-12-29 | — | — | WO | claimed |
| US-7223606-B2 | Methods of detecting nitrotyrosine and aminotyrosine residues of peptides and proteins | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-05-29 | — | — | US | disclosed |
| US-20060035385-A1 | Methods of detecting nitrotyrosine and aminotyrosine residues of peptides and proteins | NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR | 2006-02-16 | — | — | US | disclosed |
| WO-2005124338-A1 | METHODS OF DETECTING NITROTYROSINE AND AMINOTYROSINE RESIDUES OF PEPTIDES AND PROTEINS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2005-12-29 | — | — | WO | disclosed |