SCHEMBL169322

SCHEMBL169322

O=C(O)[C@H](Cc1ccc(O)cc1)N(I)I

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.55
CA2 P00918 1/20 0.44
CAMK2A Q9UQM7 1/20 0.44
ESR1 P03372 4/20 0.43
ESR2 Q92731 4/20 0.43
POLB P06746 1/20 0.43
FOLH1 Q04609 1/20 0.42
NAALAD2 Q9Y3Q0 1/20 0.42
TAAR1 Q96RJ0 3/20 0.41
SLC6A2 P23975 1/20 0.41
FNTA P49354 1/20 0.40
FNTB P49356 1/20 0.40
TRPV1 Q8NER1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169321 1.00 SLC7A5 (0.55) SLC7A5CA2CAMK2AESR1ESR2
Methane SCHEMBL17267562 0.98 SLC7A5 (0.53) SLC7A5CA2CAMK2AESR1ESR2
SCHEMBL10938101 0.91 SLC7A5 (0.46) SLC7A5ESR1ESR2
SCHEMBL836728 0.91 SLC7A5 (0.46) SLC7A5ESR1ESR2
SCHEMBL23610314 0.86 SLC7A5 (0.51) SLC7A5CA2CAMK2AESR1ESR2
SCHEMBL11053246 0.86 SLC7A5 (0.51) SLC7A5CA2CAMK2AESR1ESR2
SCHEMBL22615037 0.86 SLC7A5 (0.51) SLC7A5CA2CAMK2AESR1ESR2
SCHEMBL11053244 0.86 SLC7A5 (0.51) SLC7A5CA2CAMK2AESR1ESR2
SCHEMBL31723949 0.85 CYP1A2 (0.55) SLC7A5FOLH1
SCHEMBL2542276 0.83 SLC7A5 (0.56) SLC7A5CA2CAMK2AESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12546788-B2 Methods for differentiating destructive thyroiditis from other pathological conditions ASKA PHARMACEUTICAL CO., LTD. (JP) 2026-02-10 US claimed
US-12540403-B2 Stable composition for catalytic deposition of silver SWISSTO12 SA (CH) 2026-02-03 US claimed
US-12480021-B2 Composition for semiconductor process, method for preparing the same and method for preparing semiconductor device using the same SK ENPULSE CO., LTD. (KR) 2025-11-25 US claimed
US-20250345488-A1 CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-11-13 US claimed
US-20240301558-A1 STABLE COMPOSITION FOR CATALYTIC DEPOSITION OF SILVER SWISSTO12 SA (CH) 2024-09-12 US claimed
CN-116077712-B Graphene composite microsphere, preparation method thereof, embolic material and pharmaceutical preparation 北京石墨烯技术研究院有限公司 2024-08-16 CN claimed
CN-115156529-B Silver-coated copper powder and preparation method thereof 苏州大学 2024-06-28 CN claimed
CN-117554536-B Simultaneous analysis method for 15 thyroid hormones in environmental water sample 北京林业大学 2024-03-19 CN claimed
CN-117554536-A Simultaneous analysis method for 15 thyroid hormones in environmental water sample 北京林业大学 2024-02-13 CN claimed
WO-2023234809-A1 METHOD FOR PREVENTING IODINE RADIONUCLIDE DAMAGE TO THE HUMAN OR ANIMAL BODY АНДРЕЙЧУК, ВАСИЛИЙ ПЕТРОВИЧ 2023-12-07 WO claimed
WO-1997046541-A2 USE OF TRIAZINE-BASED UVAs FOR USE AS QUENCHERS IN PAPER-MAKING PROCESSES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-12-11 WO claimed
EP-0599908-B1 NEW GANGLIOSIDE DERIVATIVES FIDIA SPA (IT) 1997-03-12 EP claimed
EP-0649325-A4 ADMINISTRATION OF MEDICAMENTS TO POULTRY. SANOFI ANIMAL HEALTH INC (US) 1995-08-23 EP claimed
EP-0649325-A1 ADMINISTRATION OF MEDICAMENTS TO POULTRY SANOFI ANIMAL HEALTH, Inc. (US) 1995-04-26 EP claimed
US-5350841-A Amide derivatives of gangliocides including aminoacids or amino sulfonic acids for nervous system disorders FIDIA S.P.A. (IT) 1994-09-27 US claimed
EP-0599908-A1 NEW GANGLIOSIDE DERIVATIVES. FIDIA SPA (IT) 1994-06-08 EP claimed
US-5311841-A Administration of medicaments of poultry THAXTON, J. PAUL 1994-05-17 US claimed
WO-1994001147-A2 ADMINISTRATION OF MEDICAMENTS TO POULTRY SANOFI ANIMAL HEALTH, INC. (US) 1994-01-20 WO claimed
WO-1993003049-A1 NEW GANGLIOSIDE DERIVATIVES FIDIA S.P.A. (IT) 1993-02-18 WO claimed
EP-0378318-A1 Process for synthesis of FK-506 and tricarbonyl intermediates MERCK & CO. INC. (US) 1990-07-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540403-B2 Stable composition for catalytic deposition of silver SOD1, CA3, CA1 SLC7A5 2244/4885CA2 6/4885CAMK2A 2207/4885
US-12546788-B2 Methods for differentiating destructive thyroiditis from other pathological conditions TPO, TSHR, TH SLC7A5 1460/4885CA2 1208/4885CAMK2A 2071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.