Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871273 | 0.77 | KDM4E (0.52) | VDRKDM4EALDH1A1TYRALOX5 | |
| SCHEMBL29366879 | 0.74 | EGFR (0.47) | VDRKDM4EHSD17B10MAPTEGFR | |
| SCHEMBL63126 | 0.74 | EGFR (0.47) | VDRKDM4EHSD17B10MAPTEGFR | |
| SCHEMBL15471726 | 0.74 | BACE1 (0.53) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL13953779 | 0.74 | CNR1 (0.50) | VDRTYRALOX5MAPTBACE1 | |
| SCHEMBL6576818 | 0.73 | GFER (0.40) | ESR1ESR2LTA4HALDH1A1HPGD | |
| SCHEMBL18199330 | 0.71 | TYR (0.48) | VDRESR1KDM4EALDH1A1HPGD | |
| SCHEMBL6756665 | 0.70 | VDR (0.47) | VDRALOX5DAO | |
| SCHEMBL4405623 | 0.70 | ESR1 (0.70) | ESR1ESR2LTA4HKDM4EALDH1A1 | |
| SCHEMBL241799 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1686972-A1 | SPRAYABLE COMPOSITION FOR THE ADMINISTRATION OF VITAMIN D DERIVATIVES | Galderma Research & Development, S.N.C. (FR) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005053666-A1 | SPRAYABLE COMPOSITION FOR THE ADMINISTRATION OF VITAMIN D DERIVATIVES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-06-16 | — | — | WO | disclosed |