Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366879 | 1.00 | EGFR (0.47) | EGFRKDM4ECASP6CA12CA2 | |
| SCHEMBL22490117 | 0.85 | EGFR (0.46) | EGFRKDM4ECASP6CA12CA2 | |
| SCHEMBL4928195 | 0.85 | EGFR (0.42) | EGFRKDM4ECASP6CA12CA2 | |
| SCHEMBL5871273 | 0.82 | KDM4E (0.52) | EGFRKDM4ECASP6CA12CA2 | |
| SCHEMBL8770880 | 0.82 | TRPA1 (0.48) | EGFRMAPTSHBGVDRPDE4A | |
| SCHEMBL2601933 | 0.82 | CA1 (0.35) | EGFRKDM4ECASP6CA2TSHR | |
| SCHEMBL148755 | 0.79 | SHBG (0.48) | EGFRKDM4ECASP6TSHRRECQL | |
| SCHEMBL29741490 | 0.79 | SHBG (0.48) | EGFRKDM4ECASP6TSHRRECQL | |
| SCHEMBL11786007 | 0.79 | TTR (0.47) | EGFRKDM4ECASP6CA2CA4 | |
| SCHEMBL29942487 | 0.79 | PKM (0.55) | EGFRKDM4ECASP6CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209842-A | Polyamine synthesis method and polyamine | 深圳飞扬骏研新材料股份有限公司 | 2021-01-12 | — | — | CN | claimed |
| EP-1747213-B1 | NOVEL 7,7-DISUBSTITUTED DERIVATIVES OF (5H,9H)-6,8-DIOXABENZOCYCLOHEPTENE, PREPARATION METHOD THEREOF AND USE OF SAME IN THE SYNTHESIS OF NON-STEROIDAL VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2010-05-26 | — | — | EP | claimed |
| CN-100379779-C | Non-heating curable adhesive and method for producing molded body using same | E TEC CO LTD (JP) | 2008-04-09 | — | — | CN | claimed |
| US-7319155-B2 | 7,7-disubstituted (5H,9H)-6,8-dioxabenzocycloheptene compounds useful in the synthesis of non-steroidal analogues of vitamin D | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-01-15 | — | — | US | claimed |
| US-20070117989-A1 | Methanesulfonic acid [7-(4-nitrophenyl)-(5H,9H)-6,8-dioxabenzocyclohepten-2-yl]methyl ester; chemical intermediates | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-05-24 | — | — | US | claimed |
| EP-1747213-A1 | NOVEL 7,7-DISUBSTITUTED DERIVATIVES OF (5H,9H)-6,8-DIOXABENZOCYCLOHEPTENE, PREPARATION METHOD THEREOF AND USE OF SAME IN THE SYNTHESIS OF NON-STEROIDAL VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2007-01-31 | — | — | EP | claimed |
| US-20060119018-A1 | Cold-curing binder and process ror producing molding with the same | E-TEC CO., LTD. (JP) | 2006-06-08 | — | — | US | claimed |
| WO-2005116007-A1 | NOVEL 7,7-DISUBSTITUTED DERIVATIVES OF (5H,9H)-6,8-DIOXABENZOCYCLOHEPTENE, PREPARATION METHOD THEREOF AND USE OF SAME IN THE SYNTHESIS OF NON-STEROIDAL VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-12-08 | — | — | WO | claimed |
| CN-1703436-A | Non-heating curable adhesive and method for producing molded body using same | E TEC CO LTD (JP) | 2005-11-30 | — | — | CN | claimed |
| EP-1559732-A1 | COLD-CURING BINDER AND PROCESS FOR PRODUCING MOLDING WITH THE SAME | E-Tec Co., Ltd. (JP) | 2005-08-03 | — | — | EP | claimed |
| CN-114790131-A | Positive electrode lithium supplement additive, positive electrode plate, preparation method of positive electrode plate and lithium ion battery | 孚能科技(赣州)股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| EP-3130597-B1 | OLIGONUCLEOTIDE HAVING A NON-NATURAL NUCLEOTIDE AT THE 5'-TERMINAL | KYOWA KIRIN CO LTD (JP) | 2021-11-10 | — | — | EP | disclosed |
| CN-112209842-A | Polyamine synthesis method and polyamine | 深圳飞扬骏研新材料股份有限公司 | 2021-01-12 | — | — | CN | disclosed |
| EP-3229075-B1 | PHOTORESIST COMPOSITION, METHOD FOR MANUFACTURING SAME, AND METHOD FOR FORMING RESIST PATTERN | JSR CORP (JP) | 2021-01-06 | — | — | EP | disclosed |
| US-10725376-B2 | Pattern-forming method | JSR CORPORATION (JP) | 2020-07-28 | — | — | US | disclosed |
| US-4906693-A | Transesterification cure of thermosetting coatings | THE GLIDDEN COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0328950-A1 | Coating composition | THE GLIDDEN COMPANY (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4749728-A | HAVING HYDROXY-FUNCTIONAL AND CARBOXYLIC ESTER-FUNCTIONAL RESINS OR COMPONENTS | THE GLIDDEN COMPANY (US) | 1988-06-07 | — | — | US | disclosed |
| EP-0263259-A2 | Process and catalyst system for the trimerization of acetylene and acetylene compounds | HÜLS AKTIENGESELLSCHAFT (DE) | 1988-04-13 | — | — | EP | disclosed |
| EP-0252289-A2 | Transesterification catalysts and thermoset coatings | THE GLIDDEN COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117989-A1 | Methanesulfonic acid [7-(4-nitrophenyl)-(5H,9H)-6,8-dioxabenzocyclohepten-2-yl]methyl ester; chemical intermediates | CYP24A1, CYP2R1, VDR | EGFR 2722/4885KDM4E 486/4885CASP6 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.